Husqvarna Ab

Blueair Ab

Affibody Ab

Philogen S.p.a.

Fredrik Nilsson

Rajinder Mehra

Jens Näslund

Tove Eriksson

Dario Neri

Thomas Arnell

Lorenzo Tarli

Luciano Zardi

Barbara Carnemolla

Andreas Jonsson

Stefan Ståhl

Laura Borsi

Bushra Al-Hashimi

Cornelia Halin

Mikaela Friedman

Anna Stern Anderberg

Elin Gunneriusson

Stefan Stahl

Peter Kohl

Christian Engene

Marie Charlotte Ideström

Walter Frost

Jörgen Carlsson

Johan Axelsson

Fredrik Victorin

Hampus Nordensson Spångberg

Achim Brobeil

Christian Wannenwetsch

Air treatment device

Face mask clip

Hedge trimmer

Face mask

Pole saw

Telescopic pole saw

Treatment of lesions of pathological angiogenesis, especially tumors, rheumatoid arthritis, diabetic retinopathy, age-related muscular degeneration, and angiomas. A conjugate is used comprising a molecule that exerts a biocidal or cytotoxic effect on target cells in the lesions and an antibody directed against an extracellular matrix component which is present in such lesions. The antibody may be directed against fibronectin-2 (IL-2), doxorubicin, interleukin-12 (IL-12), Interferon-&#x3b3; (IFN-&#x3b3;), Tumor Necrosis Factor &#x3b1; (TNF&#x3b1;) or Tissue Factor protein (which may be truncated).

Compositions and methods for treatment of angiogenesis in pathological lesions

Treatment of lesions of pathological angiogenesis, especially tumors, rheumatoid arthritis, diabetic retinopathy, age-related muscular degeneration. and angiomas. A conjugate is used comprising a molecule that exerts a biocidal or cytotoxic effect on target cells in the lesions and an antibody directed against an extracellular matrix component which is present in such lesions. The antibody may be directed against fibronectin-2 (IL-2), doxorubicin, interleukin-12(IL-12), Interferon-&#x3b3; (IFN-&#x3b3;), Tumor Necrosis Factor &#x3b1;(TNF&#x3b1;) or Tissue Factor protein (which may be truncated).

Combination fuel canister

This invention relates to polypeptides which bind to EGFR family receptors and to applications of those polypeptides in medicine, veterinary medicine, diagnosis diagnostics and imaging.

Polypeptides

Fuel canister

A polypeptide is provided, which has a binding affinity for HER2 and which is related to a domain of staphylococcal protein A (SPA) in that the sequence of the polypeptide corresponds to the sequence of the SPA domain having from 1 to about 20 substitution mutations. Nucleic acid encoding the polypeptide, as well as expression vector and host cell for expressing the nucleic acid, are also provided. Also provided is the use of such a polypeptide as a medicament, and as a targeting agent for directing substances conjugated thereto to cells overexpressing HER2. Methods, and kits for performing the methods, are also provided, which methods and kits rely on the binding of the polypeptide to HER2.

Polypeptides having binding affinity for HER2

Growing community of inventors

Stockholm, Sweden

Fredrik Nilsson