Endo Pharmaceuticals Inc.

Algos Pharmaceutical Corporation

Fredrick L Minn

Frank S Caruso

John W Lyle

The effectiveness of an anticonvulsant such as gabapentin for alleviating neuropathic pain is potentiated by a nontoxic antagonist for the N-methyl-D-aspartate receptor or nontoxic substance that blocks a major intracellular consequence of N-methyl-D-aspartate receptor activation.

Anticonvulsant containing composition for treating neuropathic pain

The analgesic effectiveness of tramadol is significantly enhanced by administering tramadol prior to, with or following the administration of an analgesia enhancer which is a nontoxic NMDA receptor blocker and/or a nontoxic substance that blocks at least one major intracellular consequence of NMDA receptor activation.

Growing community of inventors

Blue Bell, PA, United States of America

Fredrick L Minn