Dsm IP Assets B.v.

Frederik Miggelbrink

Mylene Caussette

Gregory Maufroid

The invention relates to a method for the inactivation of amylase in a solution comprisingaspartic protease by keeping the solution at a pH between 2.1 and 2.8 and at a temperature between 20&#xb0; C. and 40&#xb0; C. for a period of time sufficient to inactivate amylase for at least 95%. With this method the level of residualaspartic protease activity in the solution at the end of the heating time is at least 90%, preferably at least 95%, and the residual amylase activity is 0.05 RAU/g or lower, more preferably 0.001 RAU/g or lower, i.e. more than 99% of the amylase activity has been inactivated.

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Lille, France

Frederik Miggelbrink