St. Jude Medical, Cardiology Division, Inc.

St Jude Medical, Atrial Fibrillation Division, Inc

Frederik Henricus Matheus Wittkampf

Israel A Byrd

René Van Es

The present disclosure provides methods and systems for limiting arcing during an electroporation procedure. A method includes delivering a calibration shock using a catheter, measuring a current delivered during the calibration shock and a voltage delivered during the calibration shock, calculating, using a processing device, a calibration shock impedance based on the delivered current and the delivered voltage, calculating, using the processing device, a bridge impedance based on the calibration shock impedance and a target impedance, wherein the bridge impedance is a difference between the calibration shock impedance and the target impedance, adding an impedance in series with the catheter, the impedance being greater than or equal to the bridge impedance, and delivering a therapeutic shock using the catheter in series with the added impedance.

Systems and methods for limiting arcing in electroporation systems

The invention provides systems, methods, and apparatus for use in ablation procedures. The invention includes a generator with at least one indifferent lead and at least one catheter lead for connecting an indifferent electrode and a catheter provided with at least one electrode, a charging unit arranged to charge an amount of electrical energy and to discharge an electrical pulse of a predetermined magnitude between the two electrode leads, a power supply arranged to supply electrical energy to the charging unit, an input unit arranged for inputting an indication of the magnitude of the pulse, and a measuring unit arranged between the electrode leads for measuring at least one electrical property between the leads. Numerous additional aspects are provided.

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Lage Vuursche, Netherlands

Frederik Henricus Matheus Wittkampf