Basf Aktiengesellschaft

Sungene Gmbh & Co. Kgaa

Frederik Börnke

Uwe Sonnewald

Thomas Ehrhardt

Karin Herbers

Ralf-Michael Schmidt

Marc Stitt Nigel

Andreas Reindl

Annette Freund

Wolfgang Lein

Kirsten Deist

Bettina Tschiersch

Horst-Ekkehard Neuhaus

Shuai Chen

The invention relates to methods for generating or increasing a pathogen resistance in plants by expression, preferably pathogen-inducible expression, of a sucrose isomerase.

Methods for obtaining pathogen resistance in plants

The present invention relates to the use of a polypeptide with the biological activity of a sucrose-6-phosphate phosphatase which, if not present, brings about growth retardation symptoms and chlorotic leaves and which is encoded by the nucleic acid sequences SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 or by a functional equivalent of SEQ ID NO:1, SEQ ID NO:3 or SEQ ID NO:5 as target for herbicides. Moreover, the present invention relates to the use of the abovementioned polypeptides in a method for identifying herbicidal or growth-regulatory compounds which inhibit sucrose-6-phosphate phosphatase. Moreover, the invention relates to the use of these compounds which have been identified via the method as herbicides or growth regulators.

Sucrose-6-phosphate phosphatase as target for herbicides

The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.

Serine hydroxymethyltransferase as a target for herbicides

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Quedlinburg, Germany

Frederik Börnke