Manistee Partners LLC

Cincinnati Children's Hospital Medical Center

Manistee Therapeutics, Inc.

Frederick Ryckman

Robert L Bratzler

Martin Wand

Bradford J Shingleton

Paul A Yelton

Provided herein are prostaglandin Fanalog compositions and methods for treating migraines.

Treatment of migraines

Provided herein are prostaglandin F2alpha analog compositions and methods for treating migraines by topical administration. The method involves administering topically to a subject in need thereof a composition including a prostaglandin F2apha analog or pharmaceutically acceptable salt thereof, in an amount effective to treat migraine. The treatment may be administered prophylactically or therapeutically. Topical administration is to the epidermis, conjunctival surface or other mucous membranes, typically to a nail, the skin, the hair, the surface of the eye or the inner surface of the eyelid, and the like. The prostaglandin F2a analog can be latanoprost, isopropyl unoprostone, bimatoprost, travoprost, or tafluprost; or pharmaceutically acceptable salt thereof.

Methods, systems, devices and/or apparatus related to predicting availability of medical facility beds. Specifically, the disclosed methods, systems, devices and/or apparatus relate to determining which beds in the medical facility are available or unavailable at specific time periods (including past, present and/or future time periods).

Growing community of inventors

West Chester, OH, United States of America

Frederick Ryckman