Aeropharm Technology, Inc.

Iep Pharmaceutical Devices Inc.

Frederick A Sexton

Akwete Lex Adjei

Anthony J Cutie

Perry Arthur Genova

Richard Joel Melker

Johannes Hugo Van Oostrom

Anthony A Mancuso

Ilona Maria Schmalfuss

This invention relates to a combination drug product comprising pioglitazone hydrochloride and a biguamide, e.g. metformin. In particular, the product comprises a core of the biguamide, e.g. metformin, at least a portion thereof has a layer or coat thereon of pioglitazone.

Core formulation

This invention relates to medicinal aerosol and more formulation and more particularly, to a medicinal aerosol formulation containing rosiglitazone maleate and a fluid carrier.

Medicinal aerosol formulation

The metering valve which includes a material reservoir formed generally above a load bearing bottom hollow, with a toroidal gas chamber formed thereabout. Both the gas chamber and the material reservoir include metering spindles which allow the material to be dispensed and gas to be mixed precisely in a mixing chamber, and dispensed through an orifice.

Powder/liquid metering valve

A medicinal formulation is disclosed comprising pioglitazone or a derivative thereof. The formulation additionally comprises a fluid carrier and a stabilizer.

Disclosure is made of a method employing real-time imaging techniques such as Magnetic Resonance Imaging in order to investigate the effect of air way structures or administration and respiratory drugs when administered by oral inhalation. The information obtained from the practice of this method yields the criteria that can be used, among other things, to design more efficient aerosol drug delivery systems which optimize the amount of medicine delivered to the lung.

Method for improving lung delivery of pharmaceutical aerosols

This invention relates to a medicinal aerosol formulation and more particularly, to a medicinal aerosol formulation containing pioglitazone medicament and a fluid carrier.

A non-aqueous medicinal aerosol formulation comprising rosiglitazone maleate, a fluid carrier, and an amino acid stabilizer. The aerosol formulation may also include drug combination formulations comprising rosiglitazone maleate and a second anti-diabetic medicament.

Non-aqueous aerosol formulation comprising rosiglitazone maleate, a non-aqueous carrier, and an amino acid stabilizer

This invention relates to a medical aerosol formulation and more particularly, to a medicinal aerosol formulation containing a rosiglitazone maleate and a fluid carrier.

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Fair Haven, NJ, United States of America

Frederick A Sexton