Usv Pharmaceutical Corporation

Frederick A Golec, Jr

Joseph Auerbach

Thomas Goetzen

Shou-Nan Ueng

Process for preparing 2,2'-diacetoxy-dibenzoylperoxide by: reacting 2-acetyl-salicyloyl chloride with aqueous hydrogen peroxide in a reaction mixture medium of tetrahydrofuran and dichloromethane in the presence of an organic base; separating a dichloromethane extract; diluting the dichloromethane extract with methanol and crystallizing the anhydrous product therefrom.

Process for the preparation of aspirin peroxide

A process is provided to a unique preparation of carboalkoxy substituted or unsubstituted benzoxazole compounds from an amino-phenol compound.

Process for preparing carboalkoxy substituted benzoxazole compounds

Optical isomeric compounds having the general formula ##STR1## are prepared by: reacting by catalytic hydrogenation a compound of the formula ##STR2## with a compound of the formula ##STR3## wherein R, R.sub.1, R.sub.2 and R.sub.3 are as defined herein, to form a mixture of isomers in a ratio of L(S)L(S)&gt;D(R)L(S); and recovering the (S,S) diastereomer by selectively precipitating an acid salt of the (S,S) ester from the solution.

N-substituted amino acid derivatives

The process of preparing a compound of the formula: ##STR1## wherein, Y and Z are each H, alkyl, halo, alkoxy, trifluoromethyl, hydroxy, alkanoyloxy, or alkanoylamino;

Process for forming certain substituted phthalimidines

Compounds of the formula ##STR1## wherein, Y and Z are each H, alkyl, halo, alkoxy, trifluoromethyl, hydroxy, alkanoyloxy, or alkanoylamino;

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Ossining, NY, United States of America

Frederick A Golec, Jr