Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Commissariat a L'energie Atomique

Laboratoires Urgo

Frederic Revol-Cavalier

Yves Fouillet

Myriam-Laure Cubizolles

Patrice Caillat

Pierre Labeye

Thomas Bordy

Jean-Marc Pernot

Gilles Marchand

Serge Lecomte

Michel Lamoise

Manuel Alessio

Remco Den Dulk

Cyril Marsiquet

Laurent Davoust

Giacomo Gropplero Di Troppenburg

Celine Escoffier

Nathalie Picollet-Dahan

Francois Chatelain

Fabien Sauter

The invention relates to a method for detecting an analyte present in a liquid specimen, including: injecting the liquid specimen into a detection chamber, the detection chamber having a non-zero volume enclosing polymeric beads covered with a reagent suitable for the analyte to be detected; capturing at least one image of at least one region of the detection chamber using a sensor; processing the image acquired by the sensor, which includes determining a texture level of the acquired image; and determining a concentration of the analyte depending on the texture level determined for the image.

Method and system for detecting an analyte present in a liquid specimen

A system for preparing a calibrated volume of blood plasma that includes a plurality of parts: a device for preparing the calibrated volume of blood plasma, which is in the form of a single card; a pneumatic-type actuating system SP; a treatment and command unit UC configured such as to execute a command sequence of different pneumatic command points of the pneumatic actuation system with a view to obtaining, from a taken blood sample, the calibrated volume of blood plasma. The device includes three distinct modules: a fluidic connection module Monto which a blood sampling device may be connected; a module Mfor separation of the blood plasma contained in the blood sample; a module Mfor obtaining at least one calibrated volume of blood plasma, after separation.

Device for preparing a calibrated volume of blood plasma

A process for manufacturing a fluidic element, which consists in forming at least one fluid-permeable zone and one fluid-impermeable zone in a three-dimensional cellular material, by addition of at least one second material having a liquid initial state. The process will for example include soaking of the cellular material by the second material present in the liquid initial state, evacuating the second material present in its liquid initial state from at least one zone of the cellular material, in order to render the permeable zone.

Process for manufacturing a fluidic element and fluidic element manufactured using said process

The present invention relates to an item () having liquid (L) storage and/or discharge properties, in particular a bandage, comprising: &#x2014;a liquid-permeable proximal structure (), consisting of a material capable of inflating in the presence of liquid (L), &#x2014;a distal structure () capable of draining a liquid (L), &#x2014;a hydrophobic and non-absorbent spacer structure () extending between the distal () and proximal () structures, and being capable of locally limiting, when said material is not inflated, the exchange of liquid between the distal and proximal structures by maintaining a gap between said structures, and of authorizing a local expansion of the proximal structure in at least one zone (P) where said material is inflated in response to coming into contact with a liquid, said expansion causing the proximal and distal structure to move together locally and the transfer of said liquid from the zone of the proximal structure () having undergone expansion to the distal structure ().

Item intended to come into contact with a liquid, in particular a bandage

The device of the invention comprises a support having a surface comprising an attachment zone (Z) capable of being functionalized with a probe (A) capable of binding, according to the pH and reversibly, to a target (B) so as to attach it; a working electrode (WE) and a counterelectrode (CE) for this working electrode, arranged on the support in the vicinity of the attachment zone; and means for applying a given electric current or a given potential to said working electrode so as to cause, when said attachment zone and said electrodes are immersed in an aqueous solution, a local variation in pH in the region of said attachment zone. The method for attaching and/or detaching a target or an object according to the invention uses this device, the attachment and/or the detachment being electrochemically controlled with the working electrode.

Device and methods for coupling/uncoupling a target or an object present in a sample

Method for measuring the global ion concentration of a body fluid that comprises application of a stable DC voltage between first and second electrodes of a cell for measuring the global ion concentration of a body fluid so as to cause electrochemical hydrolysis reactions of the body fluid water to occur at the level of said first and second electrodes, measurement of a hydrolysis current generated by said electrochemical hydrolysis reactions of the water and determination of the global ion concentration of the body fluid by comparison with a previously defined calibration curve. The measuring cell comprises a fluid channel having an internal cross-section smaller than or equal to 1.5 mm.

Method and cell for measuring the global ion concentration of a body fluid

A device for measuring electrical activity of biological elements, including a substrate that has lower and upper faces and at least one through opening, the opening being delimited by a set of walls. Two plates are placed on either side of the lower and upper faces of the substrate and delimit, with the set of walls, a chamber. Each of the plates is provided, on its face lying opposite the substrate, with at least one electrode facing the opening in the substrate. Each of the plates further has at least one channel that starts inside the chamber and connects the chamber to the outside of the device, and the chamber communicates with the outside of the device only through the channels.

Device for measuring the electrical activity of biological elements and its applications

An optomechanical sensor for measuring or detecting an acceleration or a vibration in at least one direction. The sensor has a frame, and a flexible beam having two ends. A first end is attached to the frame and a second end is mobile in the at least one direction, in response to an acceleration movement of the frame. The flexible beam includes an optical guiding structure having an input and an output. The frame has N light collection elements, where N is an integer .gtoreq.2. The frame also includes a multi-mode coupler having an input facing the output of the optical guiding structure and N outputs, the coupler coupling an optical signal at the output of the optical guiding structure to the N light collection elements. The multi-mode coupler may also transform an input light beam having a maximum into a distribution having N maxima at the output of the coupler.

Growing community of inventors

Seyssins, France

Frederic Revol-Cavalier