Centre National De La Recherche Scientifique

Bayer Cropscience Ag

UniversitÉde Strasbourg

Université De Bourgogne

Synthelor Sas

Frederic R Leroux

Jean-Pierre A Vors

Sergii Pazenok

Norbert Lui

Florence Giornal

Sylvain Juge

Jerome Bayardon

Emmanuelle Remond

Hugo Laureano

Jean-Christophe Henry

Francoise Colobert

Mark James Ford

Arnd Neeff

Winfried Etzel

Elisabeth Davioud-Charvet

Don Antoine Lanfranchi

Gilles Hanquet

Thibault Gendron

Gregory Landelle

Ingrid Nicole Wenzel

Thomas Jj Muller

The present invention relates to novel 3,5-bis(fluoroalkyl)pyrazole-4-carboxylic acid derivatives and to a process for preparing 3,5-bis(fluoroalkyl)pyrazole-4-carboxylic acid derivatives and 3,5-bis(fluoroalkyl)pyrazoles.

Method for producing 3,5-bis(fluoroalkyl)-pyrazol-4-carboxylic acid derivatives and 3,5-bis(fluoroalkyl)-pyrazoles

P-chirogenic organophosphorus compounds of general formula (I), a process for the synthesis of the compounds of formula (I), and intermediate products of general formulae (II), (III) and (IV), as shown below, are involved in the synthesis of compounds (I).  Metal complexes comprising compounds (I) as ligands are also described. The compounds and complexes are useful in asymmetric catalysis by transition metal complexes or organocatalysis, especially for asymmetric hydrogenation or allylation. Compounds of general formula (I) may be useful as agrochemical and therapeutic substances, or as reagents or intermediates for fine chemistry.

P-chirogenic organophosphorus compounds

The present invention relates to a novel process for preparing 3,5-bis(fluoroalkyl)pyrazole derivatives from &#x3b1;,&#x3b1;-dihaloamines.

Process for preparing 3,5-bis(fluoroalkyl)pyrazole derivatives from &#x3b1;,&#x3b1;-dihaloamines

Novel P-chirogenic organophosphorus compounds of general formula (I), a process for the synthesis of the compounds of formula (I), and intermediate products of general formulae (II), (III) and (IV), as shown below, are involved in the synthesis of compounds (I).  Metal complexes including compounds (I) as ligands are also described. The novel compounds and complexes are useful in asymmetric catalysis by transition metal complexes or organocatalysis, especially for asymmetric hydrogenation or allylation. Compounds of general formula (I) may be useful as agrochemical and therapeutic substances, or as reagents or intermediates for fine chemistry.

A new process for the preparation of 3,5-bis(haloalkyl)-pyrazole derivatives of the general formula (I)  

Procedure for the decarboxylation of 3,5-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives

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Herrlisheim, France

Frederic R Leroux