Idenix Pharmaceuticals, Inc.

L'oreal

Centre National De La Recherche Scientifique

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

L'université Montpellier Ii

Frederic Leroy

Dominique Surleraux

Francois-Rene Alexandre

Christophe Parsy

Jean-Luc M Leveque

David Dukhan

Thierry Convard

Michel Derock

Gilles J Gosselin

Daniel P Bauer

Richard Storer

Gerard Braque

Bernard Querleux

Basile Audoly

Jean-Christophe Meillon

Andre Charon

Michel Philippe

Christian Blaise

Cyril B Dousson

Jean-Charles Barbe

Jean-Laurent Paparin

Claire Pierra

Philippe Barbarat

Denis Mariolle

Ezra Bussmann

Lukasz Borowik

Fabien Cheynis

Jean-Francois Griffon

Christophe Claude Parsy

Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula Ia or Ib, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof. 

Macrocyclic serine protease inhibitors

This invention is directed to a method for treating a host, especially a human, infected with hepatitis C, flavivirus and/or pestivirus, comprising administering to that host an effective amount of an anti-HCV biologically active pentofuranonucleoside where the pentofuranonucleoside base is an optionally substituted 2-azapurine. The optionally substituted pentofuranonucleoside, or a salt or prodrug thereof, may be administered alone or in combination with one or more optionally substituted pentofuranonucleosides or other anti-viral agents.

Purine nucleoside analogues for treating flaviviridae including hepatitis C

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A method for making semi-conductor nanocrystals, including at least the steps of:

Method for making semi-conductor nanocrystals

The present invention relates to the use of polyols of formula (I): or a salt thereof, for preventing the hair from breaking. The invention also relates to a cosmetic composition comprising at least one such polyol or a salt thereof, in a cosmetically acceptable medium, and also to a cosmetic hair treatment process using the said composition.

Use of particular polyols for preventing the hair from breaking, composition comprising them and cosmetic hair treatment process

The invention relates to a method of generating a synthesized image of a hair, comprising the following steps: The behavioral relationship may be given by the minimization of the following function: where &#x3b1;=Lkand &#x3b2;=K/g&#x3bc;L, and where L designates the length of the hair, kits spontaneous curvature, K its bending moment, &#x3bc; its linear density andthe acceleration due to gravity, {tilde over (s)} the curvilinear abscissa relative to the length of the hair, {tilde over (k)} its local curvature relative to its length and {tilde over (z)} its height relative to its length.

Method and a system for generating a synthesized image of a hair

Provided herein are phosphothiophene and phosphothiazole compounds, for example, of any of Formulae I, IA, IIA, IIIA, IVA, VA, VIA, VIIA, IB, IIB, IIIB, IVB, VB, VIB and VIIB disclosed herein, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host infected with HCV.

Phosphothiophene and phosphothiazole HCV polymerase inhibitors

Provided herein are macrocyclic serine protease inhibitor compounds, for example, of Formula I, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of an HCV infection in a host in need thereof. 

According to the process for applying reshaping to hair by use of a hair-curler, the hair-curler (1) is arranged in such a way that the perimeter along which the lock of hair (M) is rolled increases by approx. 2 to 3% when its temperature rises to pass from a starting temperature to a higher temperature which nevertheless remains lower than a relatively low limit thus avoiding the burning of the hair and/or of the scalp; the longitudinal section of the curler is sufficient to withstand the stresses imposed by elongation of the lock of hair; the lock of hair is rolled around the curler at the starting temperature so that the hair is retained against the hair-curler; the curler is raised to the said higher temperature; the hair is thus subjected to elongation ensuring an increase in the life of the reshaping applied to the hair.

Process and curler for reshaping hair

The device for the compression of a gas comprises a motor (1), a piston (2) adapted to be displaced linearly in a pump body, transmission means (T) between the motor (1) and the piston (2) adapted to convert the rotary motion generated by the motor (1) into a reciprocating translatory motion by the piston (2). Speed varying means comprising a cam (12) are provided to impart a different speed to the piston (2) of the compressor according to the resistance opposing the motor (1) during one complete admission/compression cycle, so that the resisting torque is substantially constant and so that the motor (1) operates at its maximum torque and therefore at maximum efficiency. The section of the cam (12) is determined so as to ensure substantially isothermal compression of the gas.

Compression device, particularly for the pressure filling of a container

Device for the compression and storage of air comprising, on the one hand, a reservoir (1) provided with an air discharge head (5) intended for cooperation with a container to be charged with compressed air and, on the other hand, at least one compression chamber (C1), associated with air inlet valves (19) and air ejection valves (15) and with a compression element actuated by a motor means (13) compressing the volume of the chamber (C1) between a maximum volume and a minimum volume, the ratio between the maximum volume and the minimum volume of the said chamber (C1) being from 1.2 to 20.

Device for the compression and storage of air

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Montarnaud, France

Frederic Leroy