Biotech Tools S.a.

Biotech Tools

Frederic Henot

Thierry Legon

Sabine Pirotton

Jean Duchateau

Gael Placier

Isabelle Galy-Fauroux

Nadine Questiaux

Recombinant purified DnaK&#x2014;having a ATPase activity without the addition of an other chaperone protein&#x2014;essentially free of T-cell stimulating impurities.

Method for the purification of heat shock proteins

A complex comprising at least one heat shock protein (HSP) and at least one peptide selected from the group consisting of R-QXRAA-Rwith R=peptide with 1-10 amino acids R=peptide with 1-10 amino acids X=K or R GFFYTPK (insulin 23-29) SEQ ID No 1 GFFYTPKT (insulin 23-30) SEQ ID No 2 IYPPNANK (DER p1) SEQ ID No 3 GIEYIQHNGVVQESYYR (DER P1) SEQ ID No 4 ASTTTNYT (gp120 of HIV) SEQ ID No 5 DYEYLINVIHAFQYV (PLP 56-70) SEQ ID No 6 EKLIETYFSKNYQDYEYLINVI (PLP 43-64) SEQ ID No 7 KTTICGKGLSATVT (PLP 104-117) SEQ ID No 8 HSLGKWLGHPDKF (PLP 139-151 C140 &#xf4; S140) SEQ ID No 9 PRHPIRVELPCRISP (MOG 8-22) SEQ ID No 10 DEGGYTCFFRDHSYQ (MOG 92-106) SEQ ID No 11 Ac-ASQKRPSQRHG (MBP ac1-11) SEQ ID No 12 TGILDSIGRFFSG (MBP 35-47) SEQ ID No 13 VHFFKNIVTPRTP (MBP 89-101) SEQ ID No 14 HCLGKWLGHPDKF (PLP 139-151) SEQ ID No 15 MEVGWYRSPFSRVVHLYRNGK (MOG) SEQ ID No 16 QKRAAYDQYGHAAFE (DnaJ) SEQ ID No. 17 QKRAAVDTYCRHNYG (HLA DRB1*0401) SEQ ID No. 18 QRRAAYDQYGHAAFE SEQ ID No. 19 and QRRAAVDTYCRHNYG SEQ ID No. 20.

Peptide complex

A process for the preparation of oxidized and/or demethylated antigens comprising the steps of

Demethylated and/or oxidized membrane DNA

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Brussels, Belgium

Frederic Henot