University of Pennsylvania

Inder M. Verma

Mark Hansen

Frederic Bushman

Tal Kafri

Gary Dean Wu

James Lewis

Mark Goulian

Haim H Bau

Changchun Liu

Inder M Verma

Jinzhao Song

Scott Sherrill-Mix

Karen E Ocwieja

Gary Wu

The invention features the use of a defined microbial consortia for the replacement of a gut microbiome associated with disease. In particular, the invention provides for the treatment of hyperammonemia,colitis, hepatic encephalopathy associated with cirrhosis, and inflammatory bowel disease.

Compositions comprising a defined microbiome and methods of use thereof

Provided herein include compositions comprising a primer having the nucleic acid sequence of ACeIN-F3_c, a primer having the nucleic acid sequence of ACeIN-B3_a, a primer having the nucleic acid sequence of ACeIN-B3_b, a primer having the nucleic acid sequence of ACeIN-FIP_e, a primer having the nucleic acid sequence of ACeIN-FIP_f, a primer having the nucleic acid sequence of ACeIN-BIP (or ACeIN-BIP-song), a primer having the nucleic acid sequence of ACeIN-LF; and a primer having the nucleic acid sequence of ACeIN-LB. Also provided are methods of detecting human immunodeficiency virus (HIV) nucleic acids in a sample comprising performing reverse transcription-based loop mediated isothermal amplification (RT-LAMP) on a sample using the previously disclosed compositions.

Compositions, kits, and methods to detect HIV virus

Compositions and methods comprising a defined microbiome and methods of use thereof

Growing community of inventors

Rose Valley, PA, United States of America

Frederic Bushman