Universiteit Gent

Freddy Haesebrouck

Frank Pasmans

Filip Eddy Boyen

Benedikt J Sas

Richard Ducatelle

Filip Van Immerseel

Sven Arnouts

Venessa Eeckhaut

An Martel

Margo Baele

Maxime Mahu

Elin Verbrugghe

Benedikt Sas

Filip Boyen

Margot Baele

The present invention relates tostrains and their use in diagnosis or treatment. In addition, the invention provides a vaccine against diarrheal disease, in particular swine dysentery.

Vaccine strains of brachyspira hyodysenteriae

The present invention relates to novelmutants, to a process for producing same and to vaccines containing same, wherein saidmutants are characterized in that they elicit a humoral response that can be distinguished from the humoral response elicited by the wild type strains. It is accordingly an object of the present invention to provide the use of saidmutants as serological marker strains in the vaccination of animals, in particular mammals and birds, more in particular cattle, poultry and pigs. The serological marker vaccine is of special value in animal farming and provides a (long-lasting) immunization against a wide range ofstrains. The novel mutants are non-reverting and can be used for the efficient immunization of mammals and birds.

[object Object]

The present invention relates to novelmutants, to a process for producing the same and to vaccines containing the same, wherein saidmutants are characterized in that they are not responsive to stress-related recrudescence. It is accordingly an object of the present invention to provide the use of saidmutants in the vaccination of animals, in particular mammals and birds, more in particular pigs, poultry and cattle.

The present invention relates to butyrate producing bacterial strains related to the speciesto be used in the prevention and/or treatment of intestinal health problems. The present invention therefore provides methods and compositions that overcome the problems associated with the currently used methods for administering butyric acid in the treatment of intestinal health problems in humans and/or animals.

Method for alleviating intestinal problems and novel bacterial strains therefor

The present invention relates to the isolation and cultivation of 'Candidatus' and isolates of 'Candidatus' obtainable by these methods. The present invention further relates to the use of these bacteria for the manufacture of antigen preparations and vaccines.

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Merelbeke, Belgium

Freddy Haesebrouck