Centre National De La Recherche Scientifique

Françoise Khuong-Huu

Joanna Bakala

Jérôme Bignon

Odette Drion, Legal Representative

Guy Jean Marie Potier, Legal Representative

Emile Benechie

Marie-Claude Denise Michèle Zelveyan, Legal Representative

Denyse Herlem

Catherine Marie Germaine Magnan, Legal Representative

The invention relates to pyranone derivatives of general formula (I), wherein X is chlorine, bromine or iodine and Rand Ris independently a hydrogen atom, an alkyl, cycloalkyl or alkylene, linear or branched group containing 1-20 carbon atoms, optionally substituted by a hydroxyl, amino, ether or halogen group, or Rand Rform together a cycle of 5, 6, 7 or 8 members which is optionally substituted by a hydroxyl, amino, ether or halogen group including isomers, enantiomers, diastereoisomers and the mixtures thereof. A method for preparing the inventive derivatives and the therapeutic use thereof, in particular for treating cancer, are also disclosed.

Pyranone derivatives useful for treating cancer

Growing community of inventors

Paris, France

Françoise Khuong-Huu