Cytos Biotechnology Ag

Novartis Pharma Ag

Kuros Biosciences Ag

Franziska Lechner

Martin F Bachmann

Wolfgang Andreas Renner

Alain Tissot

Peter Sebbel

Patrick Maurer

Christine Piossek

Matthias Staufenbiel

Frank Hennecke

Lars Nieba

Rainer Ortmann

Peter Frey

Nicolas Dunant

Wolfgang A Renner

Rainer Luond

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in the production of vaccines for the treatment of infectious diseases, the treatment of allergies and as a pharmaccine to prevent or cure cancer and to efficiently induce self-specific immune responses, in particular antibody responses.

Molecular antigen array

The invention provides compositions and processes for the production of ordered and repetitive antigen or antigenic determinant arrays. The compositions of the invention are useful for the production of vaccines for the prevention of infectious diseases, the treatment of allergies and the treatment of cancers. Various embodiments of the invention provide for a core particle that is coated with any desired antigen in a highly ordered and repetitive fashion as the result of specific interactions.

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Zurich, Switzerland

Franziska Lechner