Pfm Medical Ag

Children's Medical Center Corporation

Pfm Produkte Fur Die Medizin Aktiengesellschaft

Other

Boston University

National Institutes of Health (nih), U.S. Dept. of Health and Human Sevices (ddhhs), the United States of America

Dupont, Pierre

Franz Freudenthal

Thomas Schmitz-Rode

Rolf W Günther

Pedro J Del Nido

Nikolay V Vasilyev

Alex Javois

Georg Siegner

Pierre DuPont

Malte Neuss

Pierre E Dupont

Thilo Wack

Nikolav V Vasilyev

Jinlan Huang

Christoph Boosfeld

Ales Javois

The invention relates to a device for the dosed dispensing of an infusion fluid, in particular for administering an infusion for a patient, comprising a fluid vessel for accommodating the infusion fluid, and comprising an infusion line which is arranged between the fluid vessel and a patient access during the use of the device, wherein the fluid vessel and the infusion line are connected to one another, and the infusion line is designed such that at least a sub-section of the infusion line has a predefined inner diameter and a predefined length, such that the amount of infusion fluid accommodated in the fluid vessel is dispensed to the patient access over a predetermined time period in a manner dependent on a predefined height at which the fluid vessel is arranged above the patient access.

Device for the dosed dispensing of an infusion fluid

A tissue clip for adjoining tissues including a body portion, a biasing mechanism interconnecting the body portion to a tissue grasping mechanism, the grasping mechanism having a first condition wherein the grasping mechanism is extending against and away from the body portion and a second condition wherein the grasping mechanism is biased against the body portion. A tissue clip and deployer combination. A method of interconnecting tissue by deploying the tissue clip, puncturing tissue to be interconnected with the tissue clip, and interconnecting the tissue. A method of treating an aneurism by deploying the tissue clip at an aneurism site, closing off the aneurism site with the tissue clip, and treating the aneurism. A method of imaging a surgical procedure with ultrasound by modifying a surface of a metal surgical instrument, and imaging the metal surgical instrument with ultrasound during a surgical procedure.

Tissue clip

The invention relates to a device for closing an atrial appendage, particularly the left atrial appendage, comprising a closing element, designed to be arranged in an atrial appendage entrance and to prevent an entrance of blood into the atrial appendage and/or a leakage of thrombus out of the atrial appendage, which is configured that it does not, in the implanted state, protrude out of the atrial appendage into the atrium of the heart; a first anchoring element, which is arranged adjacent to the closing element and connected to the closing element, wherein the first anchoring element is designed for an anchoring on an atrial appendage tissue wall, a connecting element which is at least in a radial direction flexible and connected to the first anchoring element and a second anchoring element, which is connected to the connecting element and designed for an anchoring on an atrial appendage tissue wall.

Device for closing an atrial appendage

Disclosed is an implantable device () to be used in a human and/or animal body for occluding or partially occluding defective openings, hollow spaces, organ tracts, etc. or creating a defined connecting opening between walls, organs, hollow spaces, etc. Said implantable device () comprises a support structure which has a great length-to-width ratio along an axis () in a first operating state (primary shape) while having a smaller length-to-width ratio along said axis () in a second operating state (secondary shape). The support structure is provided with a proximal () and a distal section () and is formed from a single wire-type element () by intercoiling and/or intertwining and/or interweaving like a tissue and/or a cluster and/or a net. Also disclosed is a placing system especially for such an implantable device, comprising an advancing element (), a directing wire () and/or an inner mandrin, and at least one holding wire (). The directing wire () and the at least one holding wire () are used for cooperating with a proximal end of the implantable device (), the implantable device () being transformable from a primary shape into a secondary shape and vice versa by moving the holding wire () and the directing wire () relative to the advancing element ().

Implantable device

In an embolization device () with a main body () and with at least one thrombogenic fiber (), which main body can be converted from an elongate primary shape to a secondary shape, the at least one thrombogenic fiber () is arranged in a configuration wound around the main body. In a method for producing an embolization coil of this kind, a primary coil () forming a main body () of the embolization coil () has at least one thrombogenic fiber () wound around it, and the primary coil () is converted in shape to a secondary coil.

Embolization device

The invention relates to an implantable device for use in the human and/or animal body to replace an organ valve, comprising a main body having a first end and a second end, wherein the first end and the second each have an opening to provide a fluid connection through the main body between the first end and the second end; a first membrane element arranged inside or at one end of the main body, wherein the membrane element is formed in such a manner that it allows the fluid connection through the main body in a first flow direction and blocks the same in a second flow direction opposite the first flow direction; wherein the main body has a large ratio of length to transverse expansion along the longitudinal axis of the main body in a first operating state (primary form) and a smaller ratio of length to transverse expansion along the longitudinal axis of the main body in a second operating state (secondary form); and wherein the main body can be reversibly transferred from the secondary form to the primary form counter to elastic material forces by the application of a force; and wherein the main body is formed from a single wire-like element or from a plurality of wire-like elements connected to each other by means interlocking winding and/or twisting and/or weaving in the manner of a woven and/or layered fabric and/or net.

Implantable device for use in the human and/or animal body to replace an organ valve

Medical device

In an implantable device () for use in the human and/or animal body for closure or partial closure of defect openings (), cavities, organ passages etc or for providing a defined communicating opening between walls, organs, cavities etc comprising a carrier structure () which in a primary form has a large ratio of length to transverse extent along an axis (x) and in a secondary form has a smaller ratio of length to transverse extent along the axis (x), wherein the carrier structure () has a proximal and a distal portion () and is formed in the manner of a weft and/or mesh and/or layered cloth and/or gauze, at least the one portion () in the secondary form has a first part () facing outwardly away from the other portion () or towards same and a second part () which deploys first from the primary form into the secondary form and which is folded back in a direction towards the other portion () or inwardly on to the first part ().

A left atrial appendage occlusion device including an occluder disk configured to substantially prevent blood from at least one of entering and exiting the left atrial appendage, a middle portion including a coiled element and a first anchoring element. The coiled element connects to the occluder disk, has a substantially constant cross section and allows for variable length, variable orientation, and/or varied angles. The first anchoring element connects to the coiled element and includes scalloped edges that are configured to anchor the occlusion device to inner walls of the left atrial appendage and reduce the risk of one of penetration and perforation of walls of the left atrial appendage. The left atrial appendage occlusion device may also include a self-centering element that connects to the occluder disk and middle portion and is configured to center the occlusion device within the orifice of the left atrial appendage.

Left atrial appendage occlusion device

A snare device for capturing an object or for cutting tissue in the body of a human or animal. The device employs at least one twisted loop of memory shaped material housed in and movable relative to a hollow member such as a catheter. The device and method of employment is particularly well adapted for retrieving objects from internal body cavities and cutting tissue therein.

Snare mechanism for surgical retrieval

In a device () for recanalizing a cavity, organ path or vessel () which is at least partially occluded by at least one compressible occlusive object, in particular a thrombus or embolus (), in the body of a human or animal, using at least one compressible and self-expanding stent () having a distal () and a proximal end (), the at least one stent () is embodied substantially in a bell shape with a widened distal end () and a constricted proximal end ().

Growing community of inventors

La Paz, Bolivia

Franz Freudenthal