Medtronic, Inc.

The Perkin-elmer Corporation

Frans M Everaerts

Paul V Trescony

Mark W Torrianni

Frank J L Everaerts

Theo P Verheggen

Wilfred Den Hartog

Kenneth Ogan

The present invention provides an electrophoretic system, apparatus, and method of use thereof for the preparation of a tissue-derived bioprosthesis.

Process for producing decellularized biological tissues

The basic concept of this invention involves the use of a wire or capillary tube as a template strand. The outside diameter and shape of the template strand correspond to the inside diameter and shape of a desired separation capillary. A detector may be incorporated by providing a pair of electrode wires, or the ends of a pair of optical fibers, and pressing them against opposite sides of the template. As plastic is then polymerized around this asssembly by casting or molding. The template is then removed, leaving a capillary channel with a sidewall incorporating the wire electrodes and optical fibers. Using this method, it is possible to form a single unit including a separation capillary, conductivity detector, and spectroscopy detector.

Method of fabricating capillary electrophoresis separation channels

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Weert, Netherlands

Frans M Everaerts