3m Innovative Properties Company

3m Innovative Properites Company

Franklyn L Frederickson

Stephen C P Joseph

Mikhail L Pekurovsky

Richard G Hansen

Michael K Domroese

Ryan Patrick Simmers

Scott A Burton

Russell E Blette

Jameel R Qiblawi

Michael D Johnson

Ted K Ringsred

Stephen C Joseph

Peter R Johnson

Adam S Cantor

Michael D Delmore

Graham M Clarke

Dennis Earl Ferguson

Mitchell A F Johnson

Jeremy K Larsen

Craig R Sykora

Robert J Devoe

Karl M Kropp

David J Wirtanen

Craig S Moeckly

Richard H Ferber

Jamieson C Keister

Kristen J Hansen

David H Brandwein

Percy T Fenn

John K Simons

Jay D Jacobs

John R Hart

A microneedle patch includes a base, at least one collapsible side wall extending from the base, and a lip disposed along the at least one collapsible sidewall and opposite the base. An adhesive is disposed along the base, and a microneedle array is affixed to the base.

Collapsible patch and method of application

A microneedle array cartridge includes a web of material having a top face and an opposite bottom face. An adhesive and a microneedle array are disposed on the bottom face of the web of material. A container is disposed relative to the bottom face of the web of material, and has a perimeter portion and a central portion for covering at least part of the microneedle array. At least part of the perimeter portion of the container contacts the adhesive, and the central portion of the container does not contact the adhesive. The perimeter portion and the central portion of the container are integrally formed.

Microneedle cartridge assembly and method of applying

A microneedle application device for moving a microneedle array toward a target skin location includes a feedback sensor. The feedback sensor is operably connected to the microneedle application device, and is capable of generating an output corresponding to forces between the target skin location and the microneedle application device.

System and method for tool feedback sensing

An applicator device including a housing, an impactor for impacting a microneedle array and accelerating the microneedle array toward the target site, wherein the impactor is capable of moving along an arcuate path to move the microneedle array toward the target site. Also, an applicator device including a housing, a patch applicator pivotally supported by the housing, and a torsion spring. The patch applicator has a retaining portion and a patch contacting portion, and the patch contacting portion is capable of moving along a substantially arcuate path between a first position and a second position. The torsion spring is capable of biasing the patch applicator relative to the housing.

Microneedle array applicator device and method of array application

An applicator that has an elastic band to snap a microneedle array against skin with a predetermined force and velocity. The microneedle array, which may be pre-loaded with drug(s), is attached to the elastic band such that the band can be secured in place (e.g., wrapped around a person's arm), pulled away from the arm, and released from a suitable distance so that the microneedle array snaps back against the arm with sufficient force to cause an intended amount of penetration of microneedles. Also, a microneedle application device has an elastic band, a microneedle device, and a structure attaching the band to the microneedle device.

Microneedle array applicator and retainer

A device () for applying a microneedle array to a skin surface. The device comprises a base () defining a skin contacting plane, an array component having a skin facing side comprising a microneedle array, and at least one connecting member () having a first portion affixed through a first hinge () to the base and a second portion affixed to the array component. The connecting member has a first equilibrium position with the microneedle array in a recessed position within the device and a second equilibrium position with the microneedle array positioned so as to be able to contact a skin surface.

Device for applying a microneedle array

Microneedle devices with microneedles having a truncated tapered shape are disclosed. The microneedles of microneedle devices may also have a controlled aspect ratio. Microneedle delivery apparatus are disclosed that include drivers designed to deliver microneedles at velocities that may enhance perforation of the stratum corneum while limiting the sensation of pain experienced at the delivery site.

Microneedle devices and microneedle delivery apparatus

A process for making a microneedle array master comprises: (a) providing a photoreactive composition, the photoreactive composition comprising: (1) at least one reactive species that is capable of undergoing an acid- or radical-initiated chemical reaction, and (2) at least one multiphoton photoinitiator system; and (b) imagewise exposing at least a portion of the composition to light sufficient to cause simultaneous absorption of at least two photons, thereby inducing at least one acid- or radical-initiated chemical reaction where the composition is exposed to the light, the imagewise exposing being carried out in a pattern that is effective to define at least the surface of a plurality of microneedles. The microneedles may be solid and the outer surface of the microneedles may be characterized by at least one concave area. The master may be used to fabricate a tool for replication.

Process for making microneedles, microneedle arrays, masters, and replication tools

An applicator device () including a housing (), an impactor () for impacting a microneedle array and accelerating the microneedle array toward the target site, wherein the impactor is capable of moving along an arcuate path to move the microneedle array toward the target site. Also, an applicator device including a housing, a patch applicator pivotally supported by the housing, and a torsion spring. The patch applicator has a retaining portion () and a patch contacting portion (), and the patch contacting portion is capable of moving along a substantially arcuate path between a first position and a second position. The torsion spring is capable of biasing the patch applicator relative to the housing.

An applicator used to apply microneedle arrays to a mammal. In particular, an application device for applying a microneedle device to a skin surface comprising a flexible sheet having a raised central area attached to the microneedle device and a supporting member at or near the periphery of the flexible sheet, wherein the flexible sheet is configured such that it will undergo a stepwise motion in the direction orthogonal to the major plane of the sheet.

Low-profile microneedle array applicator

An applicator () used to apply microneedle arrays () to a mammal. In particular, an application device for applying a microneedle device () to a skin surface comprising a flexible sheet () having a raised central area () attached to the microneedle device and a supporting member at or near the periphery of the flexible sheet, wherein the flexible sheet is configured such that it will undergo a stepwise motion in the direction orthogonal to the major plane of the sheet.

Spray gun nozzle and air cap assembly

Spray gun platform mounting

The present invention provides a liquid spray gun with several improved features, including (1) non-cylindrical air passageways on air horns included in an air cap portion of a body assembly that provide improved shape and uniformity for the wide elongate stream of liquid formed by the spray gun; (2) the air cap portion of the body assembly being mounted for manual rotation on a nozzle portion of the body assembly between positions defined by stops and retained at those positions by friction; and (3) the body assembly through which passes liquid sprayed by the spray gun being molded of polymeric material and being manually releasable from a metal platform portion of the spray gun through which air is fed to passageways through the body assembly to spray the liquid.

Liquid spray gun with non-circular horn air outlet passageways and apertures

The present invention provides a liquid spray gun with several improved features, including (1) a molded polymeric possibly disposable body assembly through which passes liquid sprayed by the spray gun that is manually releasable from a metal platform portion of the spray gun through which air is fed to passageways through the body assembly to spray the liquid; (2) non-cylindrical air passageways on air horns that provide improved shape and uniformity for the wide elongate stream of liquid formed by the spray gun, and (3) an air cap portion of the body assembly mounted for manual rotation on a nozzle portion of the body assembly between positions defined by stops and retained at those positions by friction.

Growing community of inventors

White Bear Lake, MN, United States of America

Franklyn L Frederickson