Ventana Medical Systems, Inc.

Oregon Health & Science University

Roche Molecular Systems, Inc.

Franklin Ventura

Michael S Barnes

Joe W Gray

Christophe Chefd'hotel

Thomas M Grogan

David Chafin

Benjamin C Stevens

Karl Eric Garsha

Kandavel Shanmugam

Esteban Roberts

Brian Jay Druker

Thomas Jacob

Damien Ramunno-Johnson

Matthew Mette

Alexander Schmelzer

Denny Osswald

James E Phillips-Portillo

Tothu Tania Vu

Curtis C Rose

Clayton Reynolds

Megan E Creasey

Tania Vu

A slide carrier includes: a base support; and a slide platform having a surface that is parallel to a first plane defined by a first vector and a second vector, wherein a vector extending in a direction opposite to the direction of gravity is normal with respect to a second plane defined by a third vector and a fourth vector, an angle between the first vector and the third vector is greater than zero degrees and less than 90 degrees, and an angle between the second vector and the fourth vector is greater than zero degrees and less than 90 degrees.

Pathology slide automation system and method

A gripper system includes: a first gripper finger having a first groove, a second groove, and a third groove; and a second gripper finger having a first groove, a second groove, and a third groove, wherein the gripper is configured to apply a first compression force against length edges of a slide in a widthwise direction at the first grooves, the gripper is configured to apply a second compression force against width edges of the slide in a lengthwise direction at the second grooves, the gripper is configured to apply a third compression force against width edges of the slide in a lengthwise direction at the third grooves, and the third compression force against the width edges of the slide in the lengthwise direction is an orientation in which the slide is rotated perpendicular to an orientation corresponding to a gripping position of the second grooves.

Methods, systems, and apparatuses for detecting and describing heterogeneity in a cell sample are disclosed herein. A plurality of fields of view (FOV) are generated for one or more areas of interest (AOI) within an image of the cell sample are generated. Hyperspectral or multispectral data from each FOV is organized into an image stack containing one or more z-layers, with each z-layer containing intensity data for a single marker at each pixel in the FOV. A cluster analysis is applied to the image stacks, wherein the clustering algorithm groups pixels having a similar ratio of detectable marker intensity across layers of the z-axis, thereby generating a plurality of clusters having similar expression patterns.

Methods, systems, and apparatuses for quantitative analysis of heterogeneous biomarker distribution

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Tucson, AZ, United States of America

Franklin Ventura