Neurosearch A/s

N.v. Organon

Painceptor Pharma Corporation

Frank Wätjen

Lene Teuber

Alex Haahr Gouliaev

Naheed Mirza

Andrew Cooke

Thomas Varming

William Dalby Brown

Susan Elizabeth Napier

Niall Morton Hamilton

Klaus Snej Jensen

Brian Frøstrup

Morag Ann MacCall Easson

This invention relates to novel (1R,2R,3S,5S)-2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts, such as L-tartrate monohydrates and anhydrates, wherein the salts are useful as monoamine neurotransmitter re-uptake inhibitors. Additionally, the invention also relates to the use of these salts in a method for therapy and to pharmaceutical compositions comprising the salts of the invention.

2-methoxymethyl-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octane tartrate salts

This invention relates to novel 1,5,7-trisubstituted benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAreceptor complex.

[object Object]

The present invention is directed to a method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives.

Method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives

This invention relates to novel piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

Piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

This invention relates to the use of compounds capable of inhibiting the activity of a proton-gated cation channel in the treatment of alleviation of diseases or disorders associated with, or mediated by a drop in extra cellular pH.

Inhibitors of proton-gated cation channels and their use in the treatment of ischaemic disorders

Growing community of inventors

Farum, Denmark

Frank Wätjen