Leica Microsystems Cms Gmbh

Leica Microsystems Heidelberg Gmbh

Leuze Electronic Gmbh + Co Kg

Frank Schreiber

Volker Seyfried

Bernd Widzgowski

Holger Birk

Bernhard Feller

Ingo Boehm

Patric Mrawek

Roland Seifert

Dirk-Oliver Fehrer

Rolf Brunner

Lioba Kuschel

Andreas Jüttner

Reiner Pelzer

A detector device is designed to capture light and to generate electrical signals. The detector device includes a housing and a detector disposed in the housing so as to be moveable at least partially in the housing and with respect to the housing. The detector device is useable in a detection system and/or in a microscope.

Detector device with improved signal-to-noise ratio comprising a detector in a housing moveable against a force of a spring device

A method for suppressing a spurious pulse following a measurement pulse in a measurement signal using a circuit includes generating a square-wave signal from the measurement signal. A delayed square-wave signal is generated by delaying the square-wave signal by a time span &#x3c4;. The delayed square-wave signal is input into a control input of a switching arrangement. The measurement signal or a signal derived therefrom is input into an input of the switching arrangement. The signal at the input of the switching arrangement is switched to a first output of the switching arrangement based on the delayed first square-wave signal at the control input of the switching arrangement. The time span &#x3c4;is matched to the measurement signal such that the switching arrangement is not switched to the first output during the spurious pulse. A signal at the first output is output as an output signal of the circuit.

Circuit, system and method for suppressing a spurious pulse in a measurement signal

A method for separating detection signals in the beam path of an optical device, different signals being formed in a defined temporal sequence, is wherein a suppression or separation of signals is performed on the basis of the temporal sequence which is known or can be determined/established.

Method for separating detection signals in the beam path of an optical device

A detector apparatus that is embodied to receive light and to generate electrical signals has a housing and a detector arranged in the housing. The detector includes a light sensor that is embodied to receive light and to release electrons. The light sensor is at a lower electrical potential level than the housing; and that the detector is in thermally conductive contact with the housing via an electrically insulating intermediate arrangement, the thermal conduction direction inside the housing being opposite to the light propagation direction of the light to be detected.

Detector apparatus

A microscope, in particular a confocal microscope, has one or more lasers for generating an illumination light for a sample and has a detection device for detected signals from the sample. The detection device includes multiple adjustable spectral detection channels for the detection of predefinable different wavelength regions, and is configured and refined in the interest of particularly versatile utilization in consideration of a wide variety of phenomena, with particularly good separation of the phenomena in the context of investigation, in such a way that multiple temporal detection windows are respectively settable for the spectral detection channels.

Microscope and a method for examining a sample using a microscope

A laser microscope () having a laser light source () which generates laser light pulses () for the purpose of examining a sample (). An optical element () is arranged in the beam path of the laser light pulses (). The optical element () disperses the wavelength spectrum of the laser light pulses (). Fractions () of the broad-band laser light pulses () having different wavelengths travel different path lengths upon passing through a compensation device (), such that the different fractions () arrive at the sample () at the same time.

Apparatus for temporal displacement of white light laser pulses

A device for distributing illumination light and detected light in a microscope includes a distributor optic configured to guide illumination light onto a sample and guide detected light proceeding from the sample onto a detector. The distributor optic includes a polarization unit disposed in a first light path and configured to convert the illumination light directed onto the sample into a first polarization state, a beam splitter disposed in the first light path and having the polarization dependence so as to guide the converted illumination light onto the sample, a first portion of the detected light back into the first light path, and a second portion of the detected light into a second light path separated from the first light path. A beam combiner is configured to combine the first portion and the second portion of the detected light and guide the first portion and second portion onto the detector.

Device and method for distributing illumination light and detected light in a microscope

A detector apparatus is configured to receive light and generate electrical signals. The detector apparatus includes a light sensor having a light incidence side and a cooling component. The cooling component is in direct contact with at least one of the light sensor, on the light incidence side, or a substrate carrying the light sensor.

Detector apparatus having a cooling component

A detector apparatus is configured to receive light and generate electrical signals. The detector apparatus includes a housing, a detector disposed in the housing and a cooling component disposed in the housing. The cooling component electrically insulates the detector with respect to the housing or is part of an insulator electrically that insulates the detector with respect to the housing.

A device () for variable deflection of light is described, encompassing a micromechanical mirror arrangement () having a plurality of light-reflecting mirror actuators (), and a control unit () with which the mirror actuators () are controllable into different reflection positions in order to vary the light deflection. The device () has a back-reflection structure (), systematically adapted to the mirror arrangement (), for reflecting back onto another portion of the mirror actuators (), in targeted fashion, the light reflected onto the back-reflection structure () from one portion of the mirror actuators ().

Device for variable deflection of light

Detector for microscope

The invention relates to a confocal microscope which illuminates a sample () by means of at least one light source. A detection light beam () is emitted from the sample (). The detection light beam () is spectrally split up in a spatial manner by the dispersive element () and subsequently formed on a photosensor chip () by means of a detection optical system (). At least one expanding optical system () is arranged in front of the dispersive element () in the direction of the detection light beam (). The expanding optical system () is embodied in such a manner that the numerical aperture of the detection optical system () is independent from the numerical aperture of the detection light beam () on the detection apertured diaphragm ().

Confocal microscope and method for detecting by means of a confocal microscope

A photosensor chip includes a light-sensitive region with a plurality of detector elements and a light-insensitive region including a buffer memory. The light-insensitive region is at least double the light-sensitive region. A charge produced at different points in time in the detector elements is successively transferred into the buffer memory for being subsequently read out by a read-out register from the buffer memory. In one embodiment, the buffer memory includes a first and second buffer memory adjoining corresponding sides of the light-sensitive region. The first and second buffer memory can be used alternatively for buffer-storage and read-out.

Photosensor-chip, laser-microscope comprising a photosensor-chip and method for reading a photosensor-chip

An apparatus, a microscope having an apparatus, and a method for calibration of a photosensor chip () are disclosed. The apparatus has a photosensor chip () which has a multiplicity of light-sensitive elements. A reference light source () is provided and directs the light at at least one part of the photosensor chip (). In addition, an open-loop or closed-loop control unit () is provided and determines and corrects variances between the individual light-sensitive elements.

Apparatus, microscope with an apparatus, and method for calibration of a photosensor chip

A scanning microscope with a first and at least one other detection channel is disclosed. The first detection channel comprises at least one first detector and the other detection channel comprises at least one other detector to detect the detection light given off by a sample. A switching mechanism is provided that selectively directs the detection light into the first or into the other detection channel.

Growing community of inventors

Dossenheim, Germany

Frank Schreiber