Airbus Operations Gmbh

Schering Aktiengesellschaft

Teva Pharmaceuticals International Gmbh

Auspex Pharmaceuticals, Inc.

Ratiopharm Gmbh

Birds Pharma Gmbh Berolina Innovative

Imphar Aktiengesellschaft

Frank Schneider

Frederik Albers

Michael Rempe

Hannes Müller

Tim Lübbert

Rudolf-Giesbert Alken

Axel Schreiner

Marc Scheel

Carsten Ohlfest

Matthias Mueller

Frank Rahn

Sonja Pawellek

Werner Skuballa

Hartmut Rehwinkel

Bernd Buchmann

Christian Seibt

Jens Geisler

Wilhelm Lutzer

Claudia Giesen

Wolfgang Frohlich

Hartwig Hennekes

Ulrich Rieger

Holger Brilsky

Juha-Matti Savola

Mark Forrest Gordon

Kai Lovis

Sascha Koenigsfeld

Fernando Lopez Holguin

Sascha Königsfeld

Matthias Müller

A water tank for operation in an aircraft includes a rigid tank shell, and a pressure compensation mechanism to equalize a pressure inside of the rigid tank shell with an environment. The pressure compensation mechanism includes a shutoff member to move between a closed position, a first open position allowing air to enter the rigid tank shell and a second open position allowing air to leave the rigid tank shell.

Pressureless water tank for operation in an aircraft, aircraft section and aircraft having a water tank

The present disclosure relates to a method for servicing an aircraft by a ground service unit. The method comprises reading a wireless parameter signal from a transponder at the aircraft, decoding the wireless parameter signal to derive at least one aircraft parameter of a water supply system and/or a waste system of the aircraft, moving a servicing equipment interface to a service panel of the aircraft, connecting the servicing equipment interface to a coupling at the service panel, servicing the aircraft via the servicing equipment interface corresponding to the at least one aircraft parameter, and writing a service parameter into the transponder at the aircraft.

Method for autonomous servicing of an aircraft, and a service panel, aircraft and system providing for autonomous servicing of an aircraft

A method for operating an on-board water supply and distribution system of an aircraft for supplying water includes a central water tank, first consumer assemblies with buffer tanks each including a heater to heat up water in the buffer tank to a disinfection temperature, pump having upstream and downstream sides to operate in supply and reverse modes, and high-pressure conduit system. The central water tank connects to the pump's upstream side. The conduit system connects the downstream side with a first consumer assembly. The method includes operating the pump in supply mode where water from the central tank goes to a first consumer assembly to fill a buffer tank, operating a buffer tank heater so water heats to a predetermined disinfection temperature, and operating the pump in reverse mode so heated water passes through a part of the conduit system and the upstream side of the pump.

Water supply and distribution system on-board an aircraft and method for self-sustaining hygienic operation of such system

A line assembly for installation in an aircraft fuselage includes a first line section having a first diameter, a second line section having a second diameter, a set of first line brackets, and a set of second line brackets. The first line brackets include a first receiving space configured to hold the first line section and a first support portion for attaching the first line brackets to a fuselage structural part. The second line brackets include a second receiving space configured to hold the second line section and a second support portion for attaching the second line brackets to the first line section. The second line section includes a higher flexibility than the first line section. The second line section is attached to the first line section through a plurality of second line brackets arranged at a distance to and independent from the first line brackets.

Modular line assembly for installation in an aircraft fuselage

A drain mast for an aircraft for discharge of water from the aircraft interior with a line which extends in a line direction from a connector end to a discharge end. The connector end can connect to another line in the interior of the aircraft, through which further line water flows into the drain mast. The discharge end can discharge water into a surrounding area of the aircraft. The line includes a plastic, into which a conductive material is embedded, by which the line can be heated electrically, by a heating current being conducted through the conductive material. A proportion of the embedded conductive material in the line increases in the line direction per length unit from the connector end of the line towards the discharge end such that the heating power which is introduced into the line per length unit increases from the connector end towards the discharge end.

Drain mast

A system for heating up water for a consumer unit in an aircraft, having a water reservoir and a control unit. The water reservoir has a heating device to heat water held in the water reservoir to a consumer temperature. The control unit controls the heating device so water in the water reservoir is automatically heated to or above a disinfection temperature at which germ formation in the water reservoir is eliminated or suppressed, and a temperature of the water in the water reservoir is maintained at or above the disinfection temperature for a disinfection period, the heating to the disinfection temperature being effected only during flight phases or portions of flight phases of the aircraft during which use of the consumer unit by a user is not to be expected. A corresponding method and an aircraft having such a system are disclosed.

System and method for heating up water for a consumer unit in an aircraft

The disclosure is directed to methods of treating dyskinesia in cerebral palsy in human patients using deutetrabenazine and its active metabolites.

Methods for the treatment of dyskinesia in cerebral palsy

Herein described are deuterated catecholamine derivatives of the general Formula I wherein, Ris deuterium, R, and Rare independently selected from hydrogen and deuterium and wherein at least one of Rand Rhas a deuterium enrichment in the range from 0.02 mol % to 100 mol % deuterium, and wherein the deuterium enrichment of Rand Ris different from each other and that the difference between the deuterium enrichment of Rand Ris at least 5 percentage points, Ris hydrogen, deuterium, Cto C-alkyl or Cto C-cycloalkyl, deuterated Cto C-alkyl or Cto C-cycloalkyl, or a group that is easily hydrolytically or enzymatically cleavable under physiological conditions, as well as their physiologically acceptable salts and their stereoisomers, enantiomers or diastereomers in optically pure form. The compounds can easily be prepared by mixing deuterated and non-deuterated compounds in a predefined ratio. The compounds show anti-Parkinson effect at lower doses and show lower side effects.

Position-specific asymmetric deuterium enriched catecholamine derivatives and medicaments comprising said compounds

The present invention concerns deuterated catecholamine derivatives as well as pharmaceuticals containing these compounds. In addition, the invention concerns the use of deuterated catecholamine derivatives as well as physiologically acceptable salts thereof, and also pharmaceutical compositions, which contain these compounds, also in combination with enzyme inhibitors, for the treatment of dopamine deficiency diseases or diseases which are based on disrupted tyrosine transport or disrupted tyrosine decarboxylase, as well as other disorders.

Deuterated catecholamine derivatives and medicaments comprising said compounds

A combined toilet grey water system for passenger transportation vehicles such as aircrafts includes a toilet bowl for receiving waste water and a basin for receiving grey water. Moreover, the system includes a flushing line and a flushing valve with an inlet and an outlet. The outlet of the flushing valve is connectable to a vacuum waste water system. The inlet of the flushing valve is connected via the flushing line to the toilet bowl. Therein, the basin is connected to the flushing line in such a way that the basin is connectable to the vacuum waste water system.

Combination of vacuum toilet and grey water system functions

Herein described are deuterated catecholamine derivatives of the general Formula (I) wherein Ris deuterium, R, and Rare independently selected from hydrogen and deuterium and wherein at least one of Rand Rhas a deuterium enrichment in the range from 0.02 mol % to 100 mol % deuterium, and wherein the deuterium enrichment of Rand Ris different from each other and that the difference between the deuterium enrichment of Rand Ris at least 5 percentage points, Ris hydrogen, deuterium, Cto C-alkyl or Cto C-cycloalkyl, deuterated Cto C-alkyl or Cto C-cycloalkyl, or a group that is easily hydrolytically or enzymatically cleavable under physiological conditions, as well as their physiologically acceptable salts and their stereoisomers, enantiomeres or diastereomers in optically pure form. The compounds can easily be prepared by mixing deuterated and non-deuterated compounds in a predefined ratio. The compounds show anti-Parkinson effect at lower doses and show lower side effects.

An arrangement for adapting the transportation behavior of material to be conveyed includes a first container, which is coupleable to a first pressure level; a second container, which is coupleable to a second pressure level; a connecting line for transporting material to be conveyed from the first container to the second container; and a pressure reduction device by which a pressure difference between the first container and the second container is controllably variable.

Arrangement for noise reduction in vacuum systems

The present invention relates to an arrangement for adapting the transportation behavior of material to be conveyed, which arrangement comprises a first container, which is coupleable to a first pressure level; a second container, which is coupleable to a second pressure level; a connecting line for transporting material to be conveyed from the first container to the second container; and a pressure reduction device by means of which a pressure difference between the first container and the second container is controllably variable.

The system for flushing a vacuum toilet contains a urinal basin having a drain, which is connected to a drain line, and a bypass line, into which the drain line discharges, and which is connectable via a suction valve to a vacuum system. By generating a main air current in the bypass line and a secondary air current in the drain line, a noise emission in the area of the urinal basin may be significantly reduced.

Growing community of inventors

Berlin, Germany

Frank Schneider