Biolink Corporation

Other

Infusaid, Inc.

Therex Corp.

Nd Partners, LLC

Metal Bellows Corporation

Therex Limited Partnership

Metal Bellows Company

Frank R Prosl

Brian K Estabrook

Gerald S Melsky

Hans-Dietrich Polaschegg

Elton M Tucker

Edward J Sampson

Klaus Sodemann

Paul J Smith

Harold M Martins

Dale E Whipple

James G Skakoon

Samir F Idriss

Gerard S Carlozzi

Joseph Megerman

Leonard J DeCant, Jr

Bradley J Enegren

Robert D Gage

Elwood F Kamperman

Charles Carswell

Richard W Hatch, Jr

Infusaid Corporation

Joseph J Szymanski

The present invention relates to inhibiting or preventing infection and protecting against patency complications after a blood catheter has been inserted in a patient comprising administering to the device a pharmaceutically effective amount of a composition comprising (A) at least one taurinamide derivative, and (B) heparin at a low concentration.

Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin

A medical blood access system used for hemodialysis treatment to enable blood withdrawal for processing of blood by an external apparatus and return the same blood to a patient, comprising an interfacial fluid conduit between the machine and patient's blood supply which is repeatedly connectable along a guided pathway passing through epidermis and subcutaneous tissue via a naturally formed tissue tract to enter blood space, providing improved patient safely, convenience, effective prophylaxis, without bleeding or tissue trauma or pain, and is executable by the patient to precisely connect and disconnect with minimal disfigurement or life restrictions, and is useable on virtually all patients soon after placement and is robust and safe to high blood flow.

Hemodialysis access system

The present invention relates to inhibiting or preventing infection and protecting against patency complications after a blood catheter has been inserted in a patient comprising administering to the device a pharmaceutically effective amount of a composition comprising (A) at least one taurinamide derivative, (B) at least one compound selected from the group consisting of biologically acceptable acids and biologically acceptable salts thereof; and (C) heparin at a low concentration.

The present invention relates to inhibiting or preventing infection and protecting against patency complications after a blood catheter has been inserted in a patient comprising administering to the device a pharmaceutically effective amount of a composition comprising:

A port device for implanting in a patient for subcutaneous access to the vascular system of the patient. The device includes a housing provided with apertures, each for receiving and retaining a needle. The housing is further provided with lock structure for locking catheters to the housing. The housing is configured internally to provide flow paths extending between needles disposed in the apertures and the catheters.

Port device for subcutaneous access to the vascular system of a patient

Improved apparatus and method for the dialysis of blood. The improved apparatus comprises a subcutaneous port and catheter assembly comprising a connector portion comprising a subcutaneous port element, and a catheter portion comprising a catheter element. The improved apparatus also comprises a novel percutaneous catheter assembly comprising a catheter portion comprising a catheter element, and a connector portion comprising an extracorporeal connector element.

Apparatus and method for the dialysis of blood

An improvement in an implantable port of the type including a housing that is implanted within a subcutaneous tissue pocket is disclosed, wherein the improvement comprises the presence of metallic silver, an inorganic silver compound, a silver salt of an organic acid, or other antimicrobial substances such as taurolidine on the surfaces of the port in contact with, or proximate to, the tissue of said pocket.

Method and apparatus for overcoming infection in a tissue pocket surrounding an implanted device

Improved apparatus for the dialysis of blood, a method for fabricating the same, and an improved method for the dialysis of blood.

Apparatus for the dialysis of blood, method for fabricating the same, and method for the dialysis of blood

An implanted single- or dual-lumen device for repeated accessing of a vessel within a body, especially for hemodialysis, plasmapheresis, and other fluid exchange therapy treatments. The device is characterized by having: no septum for sealing but uses a resilient material to form a seal; a smooth streamlined flowpath; low flow resistance; substantially no stagnation points, such that the device is easily and completely flushed; and a positive locking mechanism that accepts and retains a matching needle apparatus. The device is joined to a catheter, in most cases, such that fluids can be extracted from or injected into the vessel to be accessed. The device is designed for the high flowrates, on the order of 400 milliliters per minute, associated with hemodialysis, plasmapheresis, and other fluid exchange therapies. A corresponding straight-needle apparatus is designed to mate and lock with the access device, where alignment and open flowpath is ensured. The needle apparatus first penetrates the skin and then the access device via the seal. The access device is flexibly mounted to the body at the attached catheter allowing the access device itself to move under the skin so as to accommodate and align with the needle apparatus.

Valve and sealing means for hemodialysis access device

Biocidal locks

An implanted single or dual lumen device for repeated accessing of a vessel within a body, especially for hemodialysis, plasmapheresis, and other fluid exchange therapy treatments. The device is characterized by having: no septum for sealing but having instead a resilient material to form a seal; a smooth, streamlined flowpath with low flow resistance and substantially no stagnation points, such that the device is easily and completely flushed; optionally a gradually changing direction of flow path without introducing flow resistance or stagnation points with a change in direction of up to 20 degrees with a minimum bend radius of twice the lumen diameter or up to 30 degrees with a minimum bend radius of four times the lumen diameter; and a positive locking mechanism that accepts and retains a matching needle apparatus. The device is joined to a catheter, in most cases, such that fluids can be extracted from or injected into the vessel or vessels to be accessed. The device is designed for the high flow rates, on the order of 400 milliliters per minute, associated with hemodialysis, plasmapheresis, and other fluid exchange therapies. A corresponding needle apparatus is designed to mate and lock with the access device, where alignment and open flow path is ensured. The needle apparatus first penetrates the skin and then the access device via the seal. The access device is flexibly mounted to the body at the attached catheter allowing the device itself to move under the skin so as to accommodate and align with the needle apparatus.

Hemodialysis access apparatus

Hemodialysis access and lock device (10) and system, the device comprising an improved lock (32) formed of a resilient plug (34) surrounding an inserted needle cannula (NC) and having radial blades (40) with a tapered outer edge (42) locking to a corresponding tapered surface (44) of a surrounding shell (12) and an internal passage sealed by a duck-bill valve and a strain relief at a catheter and the system comprising one or more of such devices and corresponding hub structures (100) connectable to external fluid conduits and providing control of the needle cannula and an internal obturator (OB) associated with it.

Growing community of inventors

Duxbury, MA, United States of America

Frank R Prosl