Pall Corporation

Other

Frank R Pascale

Vlado I Matkovich

Thomas J Bormann

Thomas C Gsell

Eric J Krasnoff

Keith S Morris

Benjamin Janes Beck

YoungMihn Kim

Thomas Burchard

Stephen Guerrera

Charles P Lipari

Duane Piechocki

Andrey Ghindilis

Stephen Hart

Shirley Meserol, Legal Representative

Barry Wenz

Ralph I Preuss

A biological fluid analysis device () including a biosensor () comprising an electrochemical-enzymatic sensor including a working electrode () and a reference electrode (), is disclosed.

Biological fluid analysis device

A method for automatically processing a biological fluid is disclosed. The method includes the steps of obtaining a container having a biological fluid therein, providing a first signal and communicating with an automated control arrangement to establish flow of at least a portion of the biological fluid along a fluid flow path through a leukocyte depletion medium, providing a second signal and communicating with the automatic control arrangement to terminate flow along the fluid flow path wherein providing the second signal includes sensing the back pressure in the fluid flow path or the flow rate through the leukocyte depletion medium.

Automated method for processing biological fluid

An automated system for processing biological fluid includes a pressure differential generator, a biological fluid processing assembly, and an automated control arrangement coupled to at least one of the pressure differential generator and the biological fluid processing assembly. The automated system may include a porous medium, such as a red cell barrier medium, a leukocyte depletion medium, or a combination red cell barrier/leukocyte depletion medium. The automated system may also include a sensor producing a signal reflecting a parameter of fluid flow.

Automated system and method for processing biological fluid

The present invention provides for processing a biological fluid such as blood, to separate at least one component from the biological fluid, and to remove leukocytes from the separated component while returning the component depleted biological fluid to the source of the fluid. Illustratively, blood is obtained from a source such as a donor, and platelets are separated from the bold. Gas is separated from the flow path of the separated platelets, which are depleted of leukocytes, while platelet depleted blood is returned to the donor.

Method for separating components from a biological fluid

Automated system for processing biological fluid

Method for treating a biological fluid including transition zone material

A method for removing undesirable material including leukocytes from a biological fluid in an extracorporeal circuit comprises passing a leukocyte containing biological fluid from a patient into a container; passing a portion of biological fluid from the container through a recirculation loop including a filter assembly for removing leukocytes to leukocyte deplete the biological fluid and to pass the portion of leukocyte-depleted biological fluid into the container; passing additional leukocyte containing biological fluid from a patient into the container so that the additional fluid is mixed with leukocyte depleted biological fluid in the container to provide a mixture including leukocyte depleted and non-leukocyte depleted biological fluid; passing the mixture of biological fluid from the container; passing a portion of the mixture to the patient while passing another portion of the mixture through the recirculation loop.

Method for processing a biological fluid including leukocyte removal in

Methods, systems and devices for processing fluid provide for contacting the fluid with iodine.

Iodine disinfection method using a gaseous iodine treated porous medium

An expressor for varying the amount of fluid in a variable-volume container connected to at least one conduit includes a housing defining an enclosed chamber which can accommodate the container. The housing has at least one opening through which a conduit can extend. A pressure regulating mechanism is coupled to the housing to vary the pressure of fluid in the chamber and thereby vary the volume of the container.

Expressor

Methods and systems for processing a biological fluid and treating a separated component of the biological fluid are disclosed.

Method for processing biological fluid and treating separated component

Methods, systems, and devices for processing a biological fluid including leukocytes during cardioplegia are disclosed. A method for processing a biological fluid including leukocytes comprises passing a cardioplegia fluid through a bacterial removing filter; mixing the cardioplegia fluid with the biological fluid including leukocytes to form a cardioplegia mixture; and, passing the cardioplegia mixture through a cardioplegia mixture filter assembly to produce a leukocyte-depleted cardioplegia mixture, said assembly comprising a porous medium to remove leukocytes from the cardioplegia mixture.

Cardioplegia filter and method for processing cardioplegia fluid

Fluid processing system

Methods and devices for treating transition zone material are disclosed. Transition zone material is processed to form a supernatant layer which includes platelets and a sediment layer which includes red blood cells, and the supernatant layer is separated from the sediment layer by passing the supernatant layer through a porous medium. Once the supernatant layer has been separated from the sediment layer, gas may be separated from the supernatant layer.

Method for treating transition zone material

Processes and systems for combining multiple units of a biological fluid in independent containers into a single container are disclosed.

Growing community of inventors

Glen Cove, NY, United States of America

Frank R Pascale