Roche Diagnostics Operations, Inc.

Sulzer Management Ag

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Frank May

Olivier Elsenhans

Jürg Dual

Simon Gassmann

Vuk Siljegovic

Markus Brunner

Vulk Siljegovic

A method of evaluating a wear state of an assembly of a flow machine, in particular, of a bearing arrangement of a pump or turbine. For determining a wear characteristic, a mechanical query signal having a pre-definable signal shape is generated by a signal generator and a response signal generated from the query signal is detected using a sensor in contact with the assembly. The response signal is varied in dependence on a variation of a physical operating value of the assembly in accordance with a characteristic pattern, the wear characteristic is determined from the variation of the response signal and the wear state is evaluated using the wear characteristic.

Method for assessing a wear state of a module of a turbomachine, module, and turbomachine

A method and a micropipetting apparatus is described for dispensing a liquid volume into a vessel via pipetting needle without any contact between the needle and a liquid contained in the vessel. The method comprises forming a drop at the delivery tip of the pipetting needle, the drop being retained at the tip by adhesion forces, and ejecting the drop from the tip of the pipetting needle by focusing at the tip of the pipetting needle a mechanical excitation wave applied at an excitation point at some distance from the tip of the pipetting needle. The apparatus comprises a pipetting needle, an electromechanical transducer mechanically connected with said pipetting needle for mechanically exciting the pipetting needle with a pulse of mechanical waves that propagate through the needle, and an electrical signal generator for generating an excitation pulse signal and for applying this signal to the electromechanical transducer.

Pipetting needle

A level sensor apparatus is disclosed for detecting contact of a pipetting needle with a liquid contained in a vessel. The apparatus includes a sensor head made up of a pipetting needle, a needle holder, and an electromechanical transducer. The sensor head also has an associated mechanical resonance frequency. An electrical signal generator is used to generate a driving signal which when applied to the electromechanical transducer causes vibration of the pipetting needle at the resonance frequency. A measurement device is used to measure a parameter of a vibration signal indicative of the mechanical vibration of the pipetting needle when it is driven by the driving signal. An electronic circuit and associated computer software is provided to evaluate variation of the vibration signal with time and thus detect contact of the pipetting needle with a liquid contained in the vessel.

Level sensor apparatus for detecting contact of a pipetting needle with a liquid in a vessel

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Zurich, Switzerland

Frank May