Sartorius Stedim Biotech Gmbh

Apprentice Fs, Inc.

Frank Maggiore

Nabil Hajj Chehade

Angelo Stracquatanio

Milan Bradonjic

Ali Jaafar

John Zimmerman

Angelo Stracquatanio, Iii

Tanya Maroz

Sam Brewton

Kingsley Adarkwah

Kenny Chapman

Stefan Schlack

Paul Priebe

Robert Wright

Peter Makowenskyj

April Thelemann

Gary Dawson

Cassandra Lorio

Leon Vanwormer

Obay Alchorbaji

Sam Brewton Lee Crumpton

Emilee Cook

Ahmed Bekhit

Josh Morgan

Karl Baranov

Younge Qu

Jonathan Borgia

Russell Hirschorn

Matthew Hall

Kevin Walter

One variation of a system includes: a chassis located over a physical user interface of a production equipment unit that includes a set of physical input fields; a set of actuators coupled to the chassis; a selector manipulated by the set of actuators and interfacing with the set of physical input fields; a communication module configured to receive a command—corresponding to a virtual input entered by a remote operator at a virtual user interface representing the physical user interface and depicted within an operator portal remote from the production equipment unit—during a procedure at the production equipment unit; and a controller configured to: drive the set of actuators according to the command to manipulate the selector across a physical input field on the physical user interface and thus physically reproduce the virtual input at the physical user interface of the production equipment unit.

System for remote operation of non-networked production equipment units

A method for modifying a procedure includes: accessing an instructional block library containing a set of verified instructional blocks associated with approved digital procedures performed within a facility; accessing an unverified instructional block, authored by an operator, for a new digital procedure at the facility; detecting a set of language signals in the unverified instructional block; correlating an equipment unit language signal, in the set of language signals, with an equipment unit located within the facility; correlating an action language signal, in the set of language signals, with an action prompt related to the equipment unit; identifying a verified instructional block, in the set of verified instructional blocks in the instructional block library, as analogous to the unverified instructional block in response to the verified instructional block including language signals associated with the equipment unit and the action prompt; and inserting the verified instructional block in the new digital procedure.

Method for controlling dissemination of instructional content to operators performing procedures within a facility

One variation of the method for distributing censored videos of manufacturing procedures performed within a facility includes: accessing a video feed captured by a local device interfacing with a local operator during performance of a procedure within the facility; interpreting a set of objects depicted in the video feed based on features extracted from the video feed; accessing a minimum censorship specification for the procedure, the minimum censorship specification defining a set of object types corresponding to a first degree of censorship; identifying a subset of objects, in the set of objects, depicted in the video feed related to the procedure based on the set of object types defined in the minimum censorship specification; fogging the subset of objects in the video feed to generate a censored video feed; and serving the censored video feed to a remote viewer portal accessed by a remote viewer.

Method for distributing censored videos of manufacturing procedures performed within a facility to remote viewers

An assembly includes a single-use sterilizable bag for containing a biological material. The single-use sterilizable bag has at least one insertion opening; and at least one insertable component configured to be inserted into the single-use sterilizable bag via the at least one insertion opening. The at least one insertable component includes a positioning unit for positioning the insertable component with respect to the single-use sterilizable bag and at least one of a processing unit and a sensing unit for handling the biological material.

Insertable components for single-use containers

One variation of a method for automatically capturing data from non-networked production equipment includes: detecting a location of a mobile device within a facility, the mobile device manipulated by an operator while performing a step of an augmented digital procedure at a machine in the facility; estimating a position of a display on the machine relative to a field of view of an optical sensor in the mobile device based on the location of the mobile device and a stored location of the machine within the facility; in response to the position of the display falling within the field of view of the optical sensor, selecting an image captured by the optical sensor; extracting a value, presented on the display, from a region of the image depicting the display; and storing the value in a procedure file for the augmented digital procedure completed at the machine.

Method for automatically capturing data from non-networked production equipment

One variation of a method for augmenting a digital procedure for production of pharmacological materials with automatic verification of objects includes: initializing a digital procedure containing a sequence of instructional blocks; and populating a instructional block with a instruction in a set of formats and a set of target objects. The method further includes, in response to an operator initiating an instance of the instructional block: accessing video feeds of the operator performing the instructional block; identifying a target object in a target frame from the video feeds; extracting visual features from the target frame; calculating an identification score for the target object based on the visual features; in response to the identification score falling below a confidence threshold, applying a fiducial to the target object; and linking the target object to the fiducial in the instructional block.

Method for augmenting a digital procedure for production of pharmacological materials with automatic verification

One variation of a method for assisting execution of manual protocols at production equipment includes: identifying a site occupied by a mobile device based on a geospatial location of a device; identifying a space within the building occupied by the device based on identifiers of a set of wireless access points wirelessly accessible to the device and known locations of wireless access points within the building; loading a protocol associated with an equipment unit in the space; calculating a position of the device within the space based on positions optical features, detected in a field of view of an optical sensor at the device, relative to reference features represented in a space model of the space; and, when the position of the device falls within a threshold distance of a reference location proximal the equipment unit defined in a step of the procedure, rendering guidance for the step.

Assisting execution of manual protocols at production equipment

A method includes: via a user interface of a hub device, receiving a first set of user credentials associated with a first operator, the hub device connected to a set of mobile devices; accessing a first operator schedule defining a first scheduled manufacturing operation and a first observer of the first scheduled manufacturing operation, the first observer characterized by a first set of observer credentials; detecting disconnection of a first mobile device in the set of mobile devices from the hub device, the first mobile device associated with a first device ID; in response to detecting disconnection of the first mobile device from the hub device, associating the first device ID with the first operator; and routing a first video feed from the first mobile device to the first observer based on the first device ID and the first set of observer credentials.

System and method for remote observation in a non-networked production facility

A method for augmenting procedures at production equipment includes: linking a first description of a first step in a procedure and a capture type to a first capture field; generating a digital draft procedure comprising descriptions of steps extracted from the procedure and the first capture field specifying data capture of the first capture type from an equipment unit; generating augmented guidance for the first step in the procedure based on visual content recorded by a mobile device&#x2014;assigned to an exemplary operator&#x2014;during completion of the first step in the digital draft procedure; linking the augmented guidance to a location proximal the equipment unit based on locations of the first mobile device during completion of the first step in the digital draft procedure; and generating an augmented digital procedure based on steps in the procedure, the augmented guidance, and definitions for data capture according to the first capture field.

Method for augmenting procedures of a locked, regulated document

A single-use chamber comprising a primary subchamber containing at least one primary component configured to perform an operation comprising at least one of generation and handling of a biological material; and a secondary subchamber containing at least one of a connection to equipment external to the single-use chamber and a secondary component, wherein the external equipment and the secondary component are configured to support the operation of the at least one primary component; wherein the primary subchamber and the secondary subchamber are configured to be connected to each other so that the at least one primary component is operatively coupled to at least one of the connection and the secondary component.

Upstream and downstream processing within single-use containers

Growing community of inventors

Port Jefferson Station, NY, United States of America

Frank Maggiore