Georgia Tech Research Corporation

University of Massachusetts

Frank Loeffler

Kirsti M Ritalahti

Rosa Krajmalnik-Brown

Ivy Thomson

Derek R Lovley

Sarah Strycharz

The invention is directed to novel reductive dehalogenase genes encoding for reductive dehalogenases which are capable of dehalogenating halogenated organic compounds and may be useful in the bioremediation of pollutants. In particular, the invention provides an isolated polynucleotide of a novel vinyl chloride dehalogenase gene (bvcA). The novel vinyl chloride dehalogenase gene encodes a reductive dehalogenase that is capable of the complete reduction of vinyl chloride to ethene.

Isolated reductive dehalogenase genes

In preferred embodiments, bioremediation systems are provided that comprise electricigenic microbes that use electrons provided directly from the anode of an electrical bioremediation system to carry out reductive dehalogenation of halogenated hydrocarbon contaminants, including chlorinated solvents. The present invention also provides methods of performing in situ bioremediation of halogenated solvents in groundwater or soil through the use of the provided systems.

Systems and methods for microbial reductive dechlorination of environmental contaminants

The invention sets forth specific probes and primer pairs for such quantitative analysis and methods of obtaining template DNA from thespecies of interest. These techniques are useful in a bioremediation process to monitor and control the dechlorination of chlorinated hydrocarbons.

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Decatur, GA, United States of America

Frank Loeffler