Axis-shield As

Axis Biochemicals Asa

Axis-shield Asa

Abbott Rapid Diagnostics International Unlimited Company

Axis Research As

Frank Frantzen

Erling Sundrehagen

Lars Ørning

Arne Kristian Nordhei

Arne Ludvig Faaren

Andrew Thomas Campbell

Arve Strømsheim

Arve Strøsheim

Arve STØMSHEIM

The invention provides an enzymatic method for measuring the concentration of one or more analytes in the plasma portion of a blood derived sample, containing a first and a second component, where said second component interferes with the measurement of said first component. The method includes: i) diluting the sample with a reagent mixture; ii) substantially removing blood cells; iii) using a reagent which serves to temporarily prevent reaction of the second component, to generate a blocked second component; iv) causing the selective reaction of a constituent of each analyte to directly or indirectly generate detectable reaction products, where one of the analytes is the first component; v) monitoring the detectable reaction product or products; vi) relating an amount of the detectable product or products and/or a rate of formation of the detectable product or products to the concentration of each analyte, where the concentration of at least the first component is related to a corresponding detectable reaction product by means of estimating an un-measurable (fictive) endpoint. Step iii) may be carried out at any stage up to and including step iv) but before steps v) or vi). The reagent of step iii) may be applied to the sample separately or may be included in a reagent mixture during steps i) or iv). A corresponding kit is also provided.

Blood sample assay method

An assay cartridge has a base member () that defines at least two wells (), a pipette () positionable in at least one of the wells and a cap member () arranged to carry the pipette. The cap member can be releasably fastened to the base member. An extension member () defines at least one further well () and can be fastened to the base member such that the pipette is then positionable in at least one of the wells of the base and in the further well of the extension member.

Cutter for an assay cartridge

Assay cartridge

The invention provides a cassette-based automated assay for homocysteine.

Assay method

Labelling agents comprising boronic acid conjugates

The invention provides novel labelled boronic acid conjugates of formula ##STR1## (wherein V is a reporter moiety; W.sup.2 is a bond or an organic linker moiety;

Labelled boronic acid derivatives

Growing community of inventors

Oslo, Norway

Frank Frantzen