Hoffmann-La Roche Inc.

Novartis Ag

F. Hoffmann-La Roche Ag

Frank Dieterle

Hans Senn

Goetz Schlotterbeck

Jacky Vonderscher

Alfred Ross

Gerard Maurer

Elias Perentes

Laura Suter-Dick

Daniel Robert Roth

Olivier Grenet

Daniel Wahl

Andreas Mahl

André Cordier

Frank Städtler

Elias Prentes

The present invention is directed, in part, to a method of measuring &#x3b2;--microglobulin to assess glomerular alteration or damage of the kidney.

Use of &#x3b2;-2-microglobulin to assess glomerular alterations and damage in the kidney

The invention generally provides methods to determine the extent to which a compound interferes with steroid metabolism, comprising a novel biomarker of a felinine derivative. The invention also provides such novel felinine derivative biomarker.

Biomarker for farnesyl pathway

A method for processing a set of spectra, particularly NMR spectra, by selecting a principle spectral range, recording a plurality of principle spectra in the principal spectral range, obtaining a reference principal spectrum in the principal spectral range, carrying out, for each one of the principal spectra, a bin-wise division of the principal spectrum by the reference principal spectrum to obtain a corresponding set of spectral quotients; calculating, for at least one of the principal spectra, an associated set of statistical measures derived from the corresponding set of spectral quotients, and carrying out, for at least one of the sets of statistical measures, an outlier detection test.

Method for processing a set of spectra, particularly NMR spectra

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Basel, Switzerland

Frank Dieterle