Roche Diabetes Care, Inc.

Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

Roche Diagnostics International Ag

Preh-werke Gmbh Co. Kg

F. Hoffmann-la Roche Ag

Frank Deck

Thomas Weiss

Hans List

Ahmet Konya

Michael Fritz

Michael Keil

Claudio Immekus

Karl-Peter Ebert

Carlo S Effenhauser

Klaus-Dieter Sacherer

Heinz-Michael Hein

Hans-Peter Haar

Joachim Hoenes

Herbert Harttig

Volker Zimmer

Christian Hoerauf

Guenther Schmelzeisen-Redeker

Karl-Heinz Koelker

Klaus Peter Ebert

Oliver Kube

Uwe Kraemer

Hans-Juergen Kuhr

Karl Miltner

Herbert Argauer

Martin Frank

Heinrich Fruhstorfer

Wolfgang Petrich

Hanspeter Heiniger

Bernd Roesicke

Wilfried Schmid

Juergen Rasch-Menges

Rudolf Pachl

Richard Forster

Bruno Robert Thoes

Jochen Schulat

Matthias Koehler

Bernd Hiller

Marcus Schlothauer

Joerg Scherer

Peter Blasberg

Christoph Cronrath

Ortrud Quarder

Andrea Rittinghaus

Niels Kroeger-Lui

Joachim Jäger

Stefan Pfalz

Manfred Rufer

Mathias Jotter

Christian Hörauf

Klaus-Peter Ebert

Malte Hinrichs

Lindley Herpichboehm

Sven Winheim

Bernhard Guennewig

Alfred Kloos

Manfred Aigner

Jens Storjohann

Torsten Grunwald

Genrikh Siris

Katharina Haase

Juergen Fick

Hans-Jürgen Kuhr

Joanna Coleman

Felix Baader

Michael Kistner

Hartmut Berg

Joachim Doepper

Guenther Schmelzeizen-Redeker

Bernhard Günnewig

Günther Schmelzeisen-Redeker

A method for managing refilling a first reservoir of an ambulatory infusion system from a first container that stores a first drug and for managing refilling a second reservoir of the ambulatory infusion system out of a second container that stores a second drug is disclosed. The method includes repeatedly and automatically carrying out a filling volume assessment routine, which involves determining the expected infusion of the first drug and the second drug between the present time tand the end of an estimation time interval tand determining if the first reservoir shall be refilled and/or if the second reservoir shall be refilled at tbased on the expected infusion of the first drug and the second drug determined in step (a). Ambulatory infusion device control units and ambulatory infusion devices that are configured for carrying out such method are also disclosed.

Dosing unit refilling scheduling

A cannula cartridge for receiving a cannula includes a needle assembly, a cannula and a protector. The needle assembly is movable within the protector between first and second positions. In the first position the needle is covered by the protector and a retainer of the protector engages an engagement element of the needle hub by a form fit connection. In the second position the needle at least partially extends from the protector. An inserter can move the needle assembly between the first position and to the second position and then back to the first position. The retainer and the engagement element are configured such that a holding force of the retainer is overcome by applying forces parallel to the axis of the needle. An inventive kit that includes an inserter and a driver for moving the needle assembly and a method of manufacturing the cannula cartridge are also disclosed.

Method and devices for receiving a cannula

Disclosed is a medical system having a cartridge and an inserter. The cartridge includes a housing having an interior volume with a first guide within the interior volume. A cradle is disposed within the interior volume and is configured for mounting a medical appliance. The cradle includes a subcutaneous element and an insertion needle. The insertion needle is configured for being actuated to insert the subcutaneous element into a subject. The inserter includes a second guide configured to mate with the housing of the cartridge, and the first guide and second guide are configured to cooperate to guide the inserter into the interior volume along a guiding path defined by the first guide. The inserter is configured to removably attach to the cradle when guided into the interior volume. An insertion assembly is provided for actuating the insertion needle to insert the subcutaneous element into the subject.

Cartridge and inserter for a medical system

A sensor assembly () for detecting at least one analyte in a body fluid, a sensor patch () for use in a sensor assembly (), an electronics unit () for use in a sensor assembly () and a method for producing a sensor assembly () are disclosed. The sensor assembly () comprises:

Sensor assembly and method for detecting at least one analyte in a body fluid

A drug delivery device comprises first and second liquid drug reservoirs and first and second outlet ports. A drive is configured for expelling a first liquid drug from the first reservoir to the first outlet port and for expelling a second liquid drug from the second reservoir to the second outlet port. A memory is provided that contains a drug dosing scheme specifying a desired liquid drug type, and at least one sensor is provided that detects information concerning the type of liquid drug contained in the first and/or second reservoir. A processor receives the information from the at least one sensor and thereby determines the type of liquid drug retained in the first reservoir and/or the second reservoir, and uses the drug dosing scheme and the determined type of liquid drug to operate the drive. Associated devices this disclosure and methods are also disclosed.

Drug delivery device and transfer station

A functional medical package is disclosed having a disposable package and a sterile container removably received inside the disposable package. A subsystem is received in the sterile container and is configured to be at least partially inserted into a host. The sterile container has an insertion exit opening for the subsystem and a liner closes the insertion exit opening. The liner is attached to the disposable package and automatically peels off the insertion exit opening when the sterile container is removed from the disposable package. Also disclosed are a method of manufacturing the medical package and a method of using the medical package with an inserter.

Functional medical package and medical device for inserting at least one subsystem into a host

The invention concerns a method and an apparatus for transferring an amount of a liquid drug () from a supply container () having stored the liquid drug () to a collapsible reservoir (), the method including and the apparatus enabling the steps of:

Method and apparatus for transferring a liquid drug to a collapsible reservoir

Disclosed is a fully implantable sensor for detecting at least one analyte in a sample of body fluid. The sensor has a measurement chamber plate that receives the sample of bodily fluid and a quantum cascade laser illumination source that generates an illumination light beam in the spectral range and transmits it to the measurement chamber plate. The illumination light beam at least partially illuminates the measurement chamber plate and the measurement chamber plate generates a reflection light beam in response to the illumination by the illumination light beam. The reflection light beam at least partially illuminates the sample of body fluid within the measurement chamber plate. An optical detector detects at least one property of the reflection light beam and generates a sensor signal dependent on the presence of the analyte. A controlled evaluates the sensor signal. A method using an inventive fully implantable sensor is also disclosed.

Implantable sensor and method for detecting at least one analyte in a body fluid

This disclosure teaches a disposable inserter which includes a housing having arranged in a displaceable configuration an inserter assembly comprising a cannula assembly with a cannula, a manually operable member for displacing the inserter assembly from a retracted position to an advanced position in order to manually insert the cannula into the skin of a patient, a locking element for blocking or enabling displacement of the inserter assembly, and a coupling arrangement for coupling the disposable inserter to a reusable inserter for automatically displacing the inserter assembly from the retracted position to the advanced position in order to automatically insert the cannula into the skin of the patient.

Disposable inserter and reusable inserter for accommodating a disposable inserter

This disclosure concerns a method for removing gas and/or gas bubbles from a liquid medicament stored in a reservoir for an infusion pump device. The reservoir comprises a displacing member which is at least partly displaceable relative to the reservoir thereby enabling receiving mechanical oscillations in order to generate mechanical waves in the liquid medicament. The method comprises: providing the reservoir; and transmitting a mechanical oscillation to the displacing member of the reservoir thereby generating a mechanical wave in the liquid medicament for removing gas and/or gas bubbles from the liquid medicament.

Method and device for removing gas and/or gas bubbles from a liquid medicament stored in a reservoir

An inventive medical device includes an implantable device, such as an electrochemical sensor. The implantable device has an implantable portion configured for insertion into a patient, a contact portion configured for connection to another device, and an interconnecting portion connecting the implantable portion and the contact portion. A housing is provided that has a first part that is removably connectable with a second part to form a sterile packaging to seal the implantable portion against a surrounding environment. The first part comprises a first sealing surface and the second part comprises a second sealing surface and the first and second sealing surfaces interact to form a sealing area. The interconnecting portion of the implantable device extends through the sealing area. An inventive method of producing the medical device is also disclosed.

Medical device and method for producing a medical device

A filling aid for self-filling a cartridge from a storage vessel is disclosed. The filling aid has a housing that receives a fillable cartridge. A stopper is provided that interacts with the housing and is configured to enter the cartridge and a cannula is provided that is configured to pierce a septum of the cartridge. The housing is movable from an initial position in which the stopper is maintained outside the cartridge to an activated position in which the stopper is inserted in the cartridge and the septum is pierced by the cannula. Methods of manufacturing and using the filling aid are also disclosed.

Filling aid and methods for self-filling a cartridge

The present invention includes a system for withdrawing body fluids. The system includes a drive unit having a plunger which is moved from a resting position into a lancing position in order to carry out a lancing process and a lancing unit containing a lancet with a needle. The plunger and lancet are coupled together by a form fit in order to carry out a lancing process. The invention additionally concerns a method for temporarily extending a needle from a device for withdrawing body fluid as well as a lancing unit that can be attached to the drive unit.

System for withdrawing blood

An insertion device including an insertion needle holder and a drive mechanism for linearly moving the insertion needle holder in a puncturing direction. The insertion needle holder also includes at least one actuating element for actuating a drive mechanism. The drive mechanism converts a driving motion of the actuating element, which extends transversely or opposite to the puncturing direction, into a puncturing motion of the insertion needle holder.

Insertion device

Growing community of inventors

Niederkirchen, Germany

Frank Deck