Basf Se Corporation

Teva Pharmaceutical Industries Limited

Ciba Specialty Chemicals Corporation

Sandoz Ag

Frank Bienewald

Hans Jürg Kirner

Martin Studer

Beat Schmidhalter

Ulrich Berens

Gabriele Baisch

Reinhold Öhrlein

Stephan Burkhardt

Olof Wallquist

Pascal Hayoz

Heinz Wolleb

Thomas Ehlis

Barbara Wagner

Bernd Herzog

Jean-Charles Flores

Margherita Fontana

Jürg Haase

Jean-Luc Budry

Zhimin Hao

Hans Jörg Kirner

Rolf Pinkos

Paul Adriaan Van Der Schaaf

Dagmar Pascale Kunsmann-Keitel

Urs Siegrist

Mathieu G R Turbiez

Marta Fonrodona Turon

Mathias Düggeli

Olivier Frédéric Aebischer

Hans-Peter Jalett

Mathias Duggeli

Vadiraj Subbanna Ekkundi

Vilas N Mumbaikar

Pavel Tuzina

Ruth Lohwasser

Niranjan Paingankar

Martin Voelkert

Mathieu Turbiez

Stefan Burkhardt

Oliver Frédéric Aebischer

Wolfgang Kalb

Arno Stassen

Marta Fondrodona Turon

Oliver Frederic Aebischer

Matheiu G R Turbiez

Mathieu GR Turbiez

A process produces a mono vinyl thioether by reacting acetylene with a compound containing one thiol group and one hydroxy group, referred to as a thiol-hydroxy compound, where the reaction is performed at a pressure below 2 bars.

Process to produce a mono vinyl thioether

A process produces a mono vinyl ether, R&#x2014;O&#x2014;CH&#x2550;CH. R represents an organic group with at least three carbon atoms. The process involves reacting a mono hydroxy compound. R&#x2014;OH, with acetylene in presence of a catalyst to get a product mixture containing the mono vinyl ether, unconverted mono hydroxy compound, and the catalyst. To the product mixture, an ester is added that contains at least one ester group, X&#x2014;OC&#x2014;. X is a hydrocarbon group containing less carbon atoms than R. The remaining mono hydroxy compound R&#x2014;OH is reacted with the ester in the presence of the catalyst to get a transesterification product containing at least one ester group, R&#x2014;OC&#x2014;, and an alcohol, X&#x2014;OH. The mono vinyl ether is isolated from the product mixture obtained after the ester addition, optionally followed by purification of the mono vinyl ether by distillation.

Process to produce a mono vinyl ether

The present invention relates to compounds of the formula I wherein the substituents are as defined in claim, and their use as organic semiconductor in organic devices, like diodes, organic field effect transistors and/or a solar cells. The compounds of the formula I have excellent solubility in organic solvents. High efficiency of energy conversion, excellent field-effect mobility, good on/off current ratios and/or excellent stability can be observed, when said compounds are used in semiconductor devices or organic photovoltaic (PV) devices (solar cells).

Pyrrolopyrrole derivatives, their manufacture and use

Monomeric or polymeric compounds comprising at least one moiety of the formula (Ia) wherein X is CR, where R is H or a substituent as defined in claim, or is another ketopyrrole moiety e.g. of the formula (Ib) or (Ic) with this moiety and all other symbols are as defined in claim, show good solubility in organic solvents and excellent film-forming properties. In addition, high efficiency of energy conversion, excellent field-effect mobility, good on/off current ratios and/or excellent stability can be observed, when the polymers according to the invention are used in semiconductor devices or organic photovoltaic (PV) devices (solar cells). 

Ketopyrroles as organic semiconductors

A semiconducting layer comprising a non-polymeric quinoid heteroacene compound of the formula (I) wherein X stands for O, S or NR, each of R, R, R, R, R, R, R, R, Rbeing independently selected from hydrogen and an organic residue, or 2 or more thereof together forming one or more annealed rings, which may be substituted or unsubstituted, carbocyclic or helerocyclic, aromatic, quinoid or aliphatic, may be used e.g. for the manufacture of a diode, an organic field effect transistor, an organic thin film transistor, or a device containing a diode and/or an organic field effect transistor and/or organic thin film transistor. 

Quinoid systems as organic semiconductors

A process for the preparation of a substituted 2,2'-dithiophene is described, which process comprises the steps (a), (c) and optional steps (b) and (d): a reaction of a compound of the formula: with a suitable lithium organic compound, preferably Li-alkyl or Li-alkylamide; b) optional exchange of lithium against another metal selected from Mg1 Zn and Cu; c) reaction of the metallated intermediate obtained in step (a) or (b) with a suitable electrophil, which is COor an aldehyde (addition reaction), or a compound Y&#x2032;&#x2014;R17 or Y&#x2032;&#x2014;R18-Z (substitution reaction), where R17 and R18 are as defined in claim; and optionally d) modification of the product obtained in step (c), e.g. by introducing one or more conjugating moieties Y ring closure between suitable monovalent residues R17, exchange or extension of functional groups or substituents such as addition to carbonyl or substitution of carbonyl in R17 or R18. The products, including or corresponding polymers, are excellent conducting materials 

Substituted oligo- or polythiophenes

The present invention relates to compounds of the formula (I) wherein the substituents are as defined in claim, and their use as organic semiconductor in organic devices, like diodes, organic field effect transistors and/or a solar cells. The compounds of the formula I have excellent solubility in organic solvents. High efficiency of energy conversion, excellent field-effect mobility, good on/off current ratios and/or excellent stability can be observed, when said compounds are used in semiconductor devices or organic photovoltaic (PV) devices (solar cells). 

The invention relates to a semiconductor device comprising a compound of the formula I and of the formula XXI, wherein the symbols have the meanings defined in the specification, to the novel compounds of the formula I and XXI and to the use of such a compound as an organic semiconductor for the preparation of an electronic device, and further compounds and devices, as well as other embodiments given in the specification. 

Organic semiconductors and their manufacture

Disclosed is the use of merocyanine derivatives of formula 

Merocyanine derivatives

Disclosed is the use of the compounds of formula 

A novel semiconductor device comprises an azaperylene organic semiconductor of the formula I wherein the substitutents are defined herein.

Azaperylenes as organic semiconductors

The invention relates to novel synthesis methods for the preparation of the intermediates, which are suitable for the preparation of statin derivatives, especially to novel synthesis methods of the intermediate of formula VI wherein Rand Rare each independently of the other hydrogen or a hydroxy-protecting group or together are a bridging hydroxy-protecting group, and Ris a carboxy-protecting group, which methods are carried out by conversion of the intermediate of formula XIX wherein Rand Rare each independently of the other hydrogen or a hydroxy-protecting group, and Ris a carboxy-protective group. 

Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives

Synthesis methods for the preparation of intermediates which are suitable for the preparation of statin derivatives, and especially to synthesis methods for the intermediate of formula (VI) wherein R' and R&#x2032; are each independently of the other hydrogen or hydroxy-protecting group, or together are a bridging hydroxy-protecting group; and Ris a carboxy-protecting group. 

Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation

The invention relates to novel synthesis methods for the preparation of the intermediates, which are suitable for the preparation of statin derivatives, especially to novel synthesis methods of the intermediate of formula VI wherein R' and R&#x2032; are each independently of the other hydrogen or a hydroxy-protecting group or together are a bridging hydroxy-protecting group, and Ris a carboxy-protecting group, which methods are carried out by conversion of the intermediate of formula XVI wherein R&#x2032; and R&#x2032; are each independently of the other hydrogen or a hydroxy-protecting group, R* and R** are each independently of the other hydrogen or an amide-protecting group, and Ris a carboxy-protecting group; which methods proceed to further new intermediates and methods for their preparation 

Process for preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives, intermediates thereof and methods for their preparation

The invention relates to novel synthesis methods for the preparation of the intermediates, which are suitable for the preparation of statin derivatives, especially to novel synthesis methods of the intermediate of formula VI wherein Rand Rare each independently of the other hydrogen or a hydroxy-protecting group or together are a bridging hydroxy-protecting group, and Ris a carboxy-protecting group, which methods are carried out by conversion of the intermediate of formula XIX wherein Rand Rare each independently of the other hydrogen or a hydroxy-protecting group, and Ris a carboxy-protective group 

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Hegenheim, France

Frank Bienewald