Abbott Laboratories Corporation

Frank A Murawski

Terrence B Mazer

Joseph E Walton

Ronita K Geckle

John J Kropczynski, Jr

Sherri A Walker

Rhonda Cole Walsh

Monty L Evans

Michael V Walsh

Barbara S Arnholt

Larry G Tucker

Daniel Hamilton

Carl Joseph Piontek

Rhonda L Cole

Gregory James Stephens

Dosage form unit is provided to deliver one or more beneficial agents into a fluid, such as liquid enteral nutritional product. The dosage form unit includes a core containing at least one beneficial agent, preferably a marker dye, which is dispersible in the fluid. The core also contains a compatible binding agent to bind the beneficial agent together. Additional components of the core may include a plasticizer, a standard flow agent, a lubricant, additional tableting aids and at least one hydrophilic agent. A latex coating encases the core. The latex coating includes a mixture containing a substantially hydrophobic base material, preferably formed from an emulsion of cellulose acetate microspheres, which is capable of defining a matrix-type membrane, and at least one hydrophilic component being dispersible in the fluid. A dispersible beneficial agent is preferred as one of the hydrophilic components of the latex coating to allow immediate release of the beneficial agent therefrom. A method of making the dosage form unit also is provided.

Sustained release dosage form unit having latex coating and method of making the same

An apparatus for modifying a liquid enteral nutritional product. The apparatus includes a chamber having an inlet and an outlet. The inlet of the chamber is constructed to be fluidly connected to a supply container containing a liquid enteral nutritional. The chamber defines an interior space. The apparatus further includes a retainer disposed in the interior space defined by the chamber. The retainer is constructed to receive one or more dosage form units of beneficial agent therein. The apparatus further includes at least one dosage form unit of beneficial agent retained by the retainer.

Apparatus for altering composition of nutritional product during enteral tube feeding

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Westerville, OH, United States of America

Frank A Murawski