Rhone-poulenc Rorer S.a.

Rhone-poulenc Sante

Francoise Soler

Claude James

Michel Evers

Daniel Reisdorf

Yves Ribeill

Daniel Lave

Norbert Dereu

Jean-Christophe Gueguen

Christele Poujade

Romaine Bouboutou

The present invention relates to new lupane dervivatives of the general formula: ##STR1## to their salts, to their preparation and to the pharmaceutical compositions which contain them.

Lupane derivatives, their preparation and the pharmaceutical

New derivatives of formula (I) in which R.sub.1 =H, halogen, alkyl, alkyloxy, CF.sub.3, NH.sub.2, alkylamino, dialkylamino, OH, CH, phenyl or phenoxy, Ar=phenyl, naphthyl, pyridyl, quinolyl, isoquinolyl, thienyl, thieno[2,3-b]thienyl or thieno[3,2-b]thienyl (these groups optionally substituted with halogen, alkyl, alkyloxy, CF.sub.3, NH.sub.2, alkylamino, dialkylamino, OH or CN), p=0, 1 or 2, and

1H, 3H-pyrrolo[1,2-c]thiazole-7-carboxamide derivatives and

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Paris, France

Francoise Soler