Mauna Kea Technologies

Centre National De La Recherche Scientifique

Université De Limoges

Manua Kea Technologies

Observatoire De Paris

Francois Lacombe

Bertrand Viellerobe

Nicolas Boularot

Aymeric Perchant

Francois Doussoux

Magalie Genet

Nicolas Lavillonniere

Margery Rothenberg

Nicholas Ayache

Alain Barthelemy

Dominique Pagnoux

Alexandre Loiseau

Frederic Berier

David Lafaille

Frédéric Louradour

Tom Vercauteren

Sandra Marti

Marie Glanc

Georges Le Goualher

Eric Gendron

Nicolas Savoire

Pedro Santos

Mickael Lelek

Chris Tihansky

David Hughett

Douchane Stefanovitch

Michaël Lelek

Display screen with transitional graphical user interface for medical imaging equipment

An endoscopy device includes several light guides (), each light guide having one or more optical fibers. The light guides are coupled with a sweeping system () arranged to direct an excitation light beam in alternation in one of the fibers of the guides from the proximal end of the guide including the one of the fibers. In this way, the proximal ends of the guides may make use of the same sweeping system, whereas the distal ends of the guides may be installed simultaneously in different zones of interest of an object or animal () under study for an almost simultaneous observation of the zones of interest. The invention also relates to an endoscopy method used in a device according to the invention. A device and a method according to the invention may be applied to quasi-simultaneous reflectance, fluorescence, multi-photon imaging of several areas of interest.

Endoscopy device and method for simultaneous observation of several zones of interest

An imaging device including an illumination module including at least one emitter for emitting at least one excitation beam, a scanning and injection module including an image guide, a proximal end and a distal end of which are linked by a plurality of optical fibers, and a scanning and injection optical system configured to alternately inject the at least one excitation beam into an optical fiber of the image guide from the proximal end of the image guide, and a detection module including at least one detector for detecting at least one luminous flux collected at the distal end of the image guide. At least one of the illumination module and the detection module is optically conjugated with the scanning and injection module by a conjugating optical fiber.

Modular imaging system, modules for this system and method implemented using this system

A method for processing images acquired in real time through a medical device, said images being loaded into a buffer, comprising the steps of: stopping the loading of the images into the buffer, processing loaded images using an incremental algorithm, displaying successively intermediate results of the processing, resuming the loading and stopping the processing based on an evaluation of said intermediate results.

Method and system for processing images acquired in real time through a medical device

An optical head includes: a point source producing an excitation beam, optical elements adapted to converge the optical beam into an excitation point located in a subsurface plane relative to the surface of a sample, the plane being perpendicular to the optical axis of the optical head; and elements for scanning the excitation point so as to define an observation field in the subsurface plane along two perpendicular scanning directions, a rapid online scanning and a slow columnar scanning. The invention includes micro-electrical mechanical systems designed to move in translation along a selected displacement at least one of the optical elements, which is mobile along a direction perpendicular to the optical axis so as to obtain at least one of the scanning directions. The invention provides the advantages of maintaining an axial illumination of the sample and of using a miniature head.

Miniature confocal optical head with integrated scanning and confocal imaging system using same

A method to perform an endoscopic biopsy includes deploying a mechanical forceps through an accessory channel of an endoscope assembly, deploying an optical probe through the accessory channel to an area of investigation, optically evaluating tissue at the area of investigation, actuating the mechanical forceps to grasp a sample of the tissue, and retrieving the mechanical forceps and the optical probe through the accessory channel of the endoscope assembly. A biopsy apparatus includes a delivery conduit, an optical probe configured to investigate the tissue upon a distal end of an optical conduit extending through the delivery conduit, and a forceps assembly slidably engaged over the optical conduit, the forceps assembly comprising jaws configured to operate between a closed position and at least one open position, wherein the jaws of the forceps are urged into the closed position as the forceps are retracted within the delivery conduit.

Multi-purpose biopsy forceps

A system for carrying out fibered multiphoton microscopic imagery of a sample () for use in endoscopy or fluorescence microscopy includes: a femtosecond pulsed laser () for generating a multiphoton excitation laser radiation; an image guide () having a number of optical fibers and permitting the sample to be illuminated by a point-by-point scanning in a subsurface plane; pre-compensating elements () for pre-compensating for dispersion effects of the excitation pulses in the image guide (), these elements being situated between the pulsed laser and the image guide (); scanning elements for directing, in succession, the excitation laser beam in a fiber of the image guide, and; in particular, an optical head () for focussing the excitation laser beam exiting the image guide in the sample ().

System and method for carrying out fibre-type multiphoton microscopic imaging of a sample

The invention relates to a method for measuring the speed of a particle such as a red blood cell moving inside a flow such as a flow of the blood, using a light scanning microscope. The inventive method comprises the following steps: acquisition of an image by x and y light scanning on a plane containing the object; detection on the plane (x, y) of a mark on the plane (x, y); estimation of the speed vof the object from the gradient thus determined.

Method and system for measuring the speed of blood flow

An imaging device includes an illumination module comprising at least one emitter for emitting at least one excitation beam; a scanning and injection module comprising an image guide, a proximal end and a distal end of which are linked by a plurality of optical fibers; a scanning and injection optical system configured to alternately inject the at least one excitation beam into an optical fiber of the image guide from the proximal end of the image guide; a detection module comprising a detector for detecting a luminous flux collected at the distal end of the image guide, wherein at least one of the illumination module and the detection module is optically conjugated with the scanning and injection module using a conjugating optical fiber.

Growing community of inventors

Chaville, France

Francois Lacombe