Laboratoires Sarget

Pierre Fabre S.a.

Societe Cortial

Francois Fauran

Gisele Prat

Claude Feniou

Annie Thibault

Henri Cousse

Gilbert Mouzin

Bernard Bonnaud

Jacqueline Mosser

Marie Charveron

Henri Combier

Claude Andre

Claude Andre-Mouries

The present invention concerns new derivatives of 1-aryl 2-aminomethyl cyclopropane carboxylates (Z), their preparation and their use as useful drugs for the treatment of various pains. The new derivatives of the present invention have the general formula I ##STR1## in which: R represents a hydrogen or halogen atom, a C.sub.1 to C.sub.4 lower alkyl group, a C.sub.1 to C.sub.4 lower alkoxy group, or a nitro, amino, sulfamoyl or hydroxy group;

1-Aryl 2-aminomethyl cyclopropane carboxylates (Z)

1-Aryl 2-aminomethyl cyclopropane carboxylates (Z) as drugs in the

Acetals and ketals of benzopyran glycosides, prepared by condensing a benzopyran glycoside with a carbonyl compound using a chloroformate ester as condensing agent, show enhanced activity in treating capillary fragility and related pathologies, as well as effectiveness in modifying the evolution of diabetic cataracts.

Benzopyran glycoside acetals and ketals

A method for reducing serum lipid levels in humans and animals is provided which comprises administering a hypolipidemically effective amount of p-chlorophenyl 2-(p-chlorophenoxy)-2-methylpropionate. A hypolipidemic composition is provided which comprises p-chlorophenyl 2-(p-chlorophenoxy)-2-methylpropionate, as principal active ingredient, in combination with a pharmaceutically acceptable carrier. Total serum lipids and serum cholesterol levels are significantly reduced.

Method and composition for reducing serum lipid levels using

A plant extract rich in triterpenic constituents obtained from chrysanthellum and containing as principle component a triterpenic saponin derivative of echinocystic acid whose glycoside contains rhamnose, glucose and xylose may be prepared by extraction of chrysanthellum plants. The extract has been shown to have pharmacological activity, especially analgesic, anti-inflammatory, capillaroprotective and anti-ulcer activity.

Chrysanthellum plant extract

3-Amino 3H-isobenzofuranones substituted on the nitrogen atom with benzodioxol-1,3, benzodioxane-1,4 or benzodioxane-1,3 rings are described which possess analgesic and anti-edematous properties.

Amino-3H-isobenzofuranones N-substitutes and their therapeutic

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Castanet-Tolosan, France

Francois Fauran