Vertex Pharmaceuticals, Inc.

Francois Denis

Tiansheng Wang

Michael Aaron Brodney

Brian Ledford

Jingrong Cao

Jon H Come

Ales Medek

Yi Shi

Suganthini S Nanthakumar

Kevin Gagnon

Warren A Dorsch

Peter Jamison Rose

Elaine B Krueger

Muna Shrestha

Timothy J Senter

Leslie A Dakin

Olivier Nicolas

Camil Sayegh

Anne Fortier

Kan-Nian Hu

Faith Witkos

Martine Hamel

The disclosure provides at least one entity chosen from compounds of formula (I), solid state forms of the same, compositions comprising the same, and methods of using the same, including use in treating focal segmental glomerulosclerosis (FSGS) and/or non-diabetic kidney disease (NDKD).

Inhibitors of APOL1 and methods of using same

The disclosure provides a compound of Formula (I), including deuterated derivatives, pharmaceutically acceptable salts, and solvates thereof, solid state forms of those compounds, compositions comprising those compounds and solid forms, and methods of using the same, including use in treating focal segmental glomerulosclerosis (FSGS) and/or non-diabetic kidney disease (NDKD). 

Growing community of inventors

Boston, MA, United States of America

Francois Denis