Commissariat a L'energie Atomique

Centre National De La Recherche Scientifique

Universitè De Montpellier

Commissariat a L'energie Atomique Et Aux Energies Alternatives

Sikemia

Universite De Montpellier Ii

Franck Martin

Michel Granier

Gérard Lanneau

Patrice Caillat

Françoise Vinet

Antoine Hoang

Marie-Line Cosnier

Guillaume Gracy

The invention relates to novel silane compounds corresponding to the formula (I) below:A-E-X&#x2003;&#x2003; (I)in which: in which: Use of these silane compounds for functionalizing solid supports and for immobilizing biological molecules on these supports.

Silane compounds and use of same for functionalizing solid supports and immobilizing biological molecules on these supports

The invention relates to novel silane compounds corresponding to the following formula (I):A-E-X&#x2003;&#x2003;(I)in which: Use of these silane compounds for functionalizing solid supports and for immobilizing biological molecules on these supports.

Silane compounds and their use in functionalizing solid supports and immobilizing biological molecules on these supports

A device () to sample molecules of biological interest is described. The device () includes capture zones () whose developed surface area is much greater than the surface so that sampling by contact allows a sufficient quantity of molecules to be obtained to achieve reliable analysis, whilst being sized so that the device () is neither invasive nor aggressive. In particular, the device comprises tiered capture zones () located on a support () fabricated using microtechnology techniques; the capture zones () may advantageously be functionalised.

Device for contact molecular sampling

The invention relates to novel silane compounds corresponding to the following formula (I): in which Rcan represent a methyl group, Rand Rcan represent a hydrogen atom, A can represent &#x2014;O&#x2014;, E can represent an alkylene group, X can represent a methoxysilane group, Z can represent a simple bond and Y can represent an &#x2014;Nor &#x2014;N&#x2014;NHgroup. Use of these silane compounds to functionalize solid supports and to immobilize biological molecules on these supports.

Silane compounds carrying a hydrazone or diazo functional group in order to functionalize solid supports and immobilize biological molecules on these supports

The invention relates to &#x3c9;-silanyl n-alkanal compounds, method for production and use thereof in the fuctionalization of solid supports, solid supports functionalized by the compounds and the use of solid supports thus functionalized for the immobilization and/or synthesis of biological molecules of interest.

Growing community of inventors

Montpellier, France

Franck Martin