Centre National De La Recherche Scientifique

Franck Choplin

Jamal Bousbaa

Bernard Benneteau

Eliane Souteyrand

Jean-Pierre Cloarec

Jean-René Martin

The invention concerns organosilicon compounds, their method of preparation and their use as coupling agents for deposition, at the surface of a solid support, an organized self-assembled monolayer. The invention also concerns a method for obtaining solid supports whereof the surface is modified by an organized self-assembled monolayer comprising a system of said organosilicon compounds, and the use of said solid supports for biomolecular synthesis or immobilization.

Organosilicon compounds, preparation method and uses thereof

This invention concerns the use, for synthesizing and immobilising nucleic acids, of a solid support modified by an organized self-assembled monolayer of one or several organosilicon compounds. The invention also concerns methods for synthesizing and immobilizing nucleic acids on such a silanized solid support, and DNA chips obtained by said methods.

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Valennes, France

Franck Choplin