Other

Stichting Centraal Diergeneeskundig Instituut

Franciscus Antonius Maria Rijsewijk

Johannes Theodorus Van Oirschot

Remco Siebren Schrijver

Disclosed and claimed is the use of a liquid jet intradermal administration apparatus that administers a composition: without a needle; and in the epidermis, dermis and/or hypodermis, such as a Pigjet apparatus, for administering bovine vaccines or immunogenic compositions, especially bovine plasmid vaccines or immunogenic compositions. Accordingly, the invention involves bovine immunogenic or vaccine compositions in such an apparatus, and methods for vaccinating bovines or for inducing an immunogenic response in bovines employing such an apparatus, as well as the apparatus containing bovine immunogenic or vaccine compositions.

Bovine polynucleotide vaccine for the intradermal route

Bovine polynucletide vaccine for the intradermal route

A deletion mutant of bovine herpesvirus type 1 which has a deletion in the glycoprotein gE-gene and which may further have a deletion in the thymidine kinase gene and/or the glycoprotein gI-gene, or have an insertion of a heterologous gene is disclosed. Recombinant nucleic acids which encode the gE-gene or a part thereof are also disclosed, in addition to vaccines and a method of treatment.

Growing community of inventors

Amsterdam, Netherlands

Franciscus Antonius Maria Rijsewijk