Max-planck-gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

Francisco Perez-Balderas

Felix Hausch

This invention relates to a method of identifying a compound capable of binding to a target domain of a G-protein coupled receptor comprising the steps of: (a) providing a receptor comprising said target domain and a first group linked to said target domain; (b) bringing into contact said receptor of (a) with a test molecule comprising a second group and said compound linked to each other, wherein said first group binds said second group; and (c) determining, subsequent to the binding of said first group to said second group, whether said compound binds to said target domain.

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Oxford, United Kingdom

Francisco Perez-Balderas