Sanofi

Sanofi Biotechnology

Sanofi-Aventis Biotechnology

Francisco Javier Jimenez Jimenez

Ramon Antonio Hernandez Vecino

Cliona Marie Molony

Emanuele De Rinaldis

Paul Bryce

Fang Zhou

Hsiaohui Wu

Anne-Gaëlle Radenac

Disclosed are methods of treating various disorders with anti-IL-4Rα antibodies and fragments thereof.

Method of treating an eye-related disorder by administering an anti-interleukin-4 receptor alpha (anti-IL-4Rα) antibody

Data processing systems for identifying new indications for a drug can include a computer-readable memory including computer-executable instructions; and at least one processor configured to execute executable logic including the computer-executable instructions and at least one machine learning model to perform one or more operations. The one or more operations can include receiving data representing medical records of a plurality of patients; selecting a set of patients; determining a plurality of patient characteristics of the set of patients; grouping, in accordance with the plurality of patient characteristics, the set of patients to generate a plurality of distinct groups, each of the distinct groups including at least one patient of the set of patients; selecting, based on one or more group selection criteria, a set of distinct groups of the plurality of distinct groups; and identifying one or more relevant patient characteristics by analyzing each distinct group of the set of distinct groups.

Data processing systems and methods for identifying new indications for drugs

Systems, methods, and computer products can predict rates of hypoglycemia in patients. One of the methods includes receiving data representing medical records of a patient, the patient having been diagnosed with diabetes mellitus. The method includes determine an predicted rate of hypoglycemic events using a machine learning system, the machine being trained using data representing the medical records of a plurality of patients and the corresponding rate of hypoglycemic events for the respective patients. The methods also includes producing the predicted rate for the patient.

Predicting rates of hypoglycemia by a machine learning system

Disclosed are methods of treating various disorders with anti-IL-4R&#x3b1; antibodies and fragments thereof.

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Brookline, MA, United States of America

Francisco Javier Jimenez Jimenez