Alza Corporation

Other

Alza Coporation

Francisco Jao

George V Guittard

Susan M Marks

David J Kidney

Fernando E Gumucio

David E Edgren

Patrick S Wong

Patrick S-l Wong

Felix T Theeuwes

Hoa T Huynh

Liang-Chang Dong

Phyllis I Gardner

Jason J Wan

Patrick S -l Wong

Yolanda M Puga

Hoa I Huynh

A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a different drug according to a therapeutic program for the management of incontinence alone, and for other therapy.

Method for the management of incontinence

The present invention is directed to a multilayered dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent to a fluid environment of use. The active agent dosage form is a multilayer core, often bilayer, formed of polymer matrices that swell upon contact with the fluids of the stomach. At least one layer of the multilayered dosage form includes an active agent. A portion of the polymer matrices are surrounded by a band of insoluble material that prevents the covered portion of the polymer matrices from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.

Gastric retention dosage form having multiple layers

The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a polymer matrix that swells upon contact with the fluids of the stomach. A portion of the polymer matrix is surrounded by a band of insoluble material that prevents the covered portion of the polymer matrix from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.

Prolonged release active agent dosage form adapted for gastric retention

The present invention is directed to an active agent dosage form and methods of its fabrication which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface one or more insoluble bands located in complementary grooves. The invention is also directed to articles of manufacture, methods and systems for fabricating the active agent dosage form.

Method of fabricating a banded prolonged release active agent dosage form

A composition comprising oxybutynin, a dosage form comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.

Oxybutynin therapy

A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.

Dosage form and method for treating incontinence

Dosage form comprising oxybutynin

A composition comprising oxybutynin and a device comprising oxybutynin are disclosed for oxybutynin therapy.

A dosage form is disclosed comprising an antiemetic and antinausea drug for treating vomiting and nausea.

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San Jose, CA, United States of America

Francisco Jao