Bial-Portela Ca & S.a.

Francisco Cardona

Laszlo Erno Kiss

Alexander Beliaev

Pedro Nuno Leal Palma

Tino Rossi

Patrício Manuel Vieira Araujo Soares Da Silva

Rui Pinto

This invention relates to: (a) compounds of formula Ia (with R1, R4 to R6, n and A as defined herein) and pharmaceutically acceptable salts or solvates thereof that are useful as dopamine-&#x3b2;-hydroxylase inhibitors; (b) pharmaceutical compositions (comprising such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) therapeutic methods of treatment using such compounds, salts or solvates; and (e) processes and intermediates useful for the synthesis of such compounds. 

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São Mamede do Coronado, Portugal

Francisco Cardona