Gist-brocades N.v.

Royal Gist-brocades N.v.

Francis Paul Buxton

David Ivor Gwynne

Mark Hudson Pickett

Claudio Scazzocchio

Roger W Davies

Roger Wayne Davies

Novel vectors are disclosed for use in filamentous fungi such as Aspergillus sp. in particular, whereby protein coding regions may be inserted therein to achieve expression or expression followed by secretion of the coded protein from the host. Signal peptide sequences and promoter sequences valuable for this purpose are disclosed as are expression vectors containing coding regions native or foreign to the fungal host. In accordance with the invention, a filamentous fungus such as Aspergillus may be provided with foreign or natural coding regions associated with foreign or natural promoter sequences and optionally signal peptide sequences which can be used to control the expression and/or secretion of the proteins encoded by these coding regions.

Vectors for use in filamentous fungi

Vectors in use in filamentous fungi

Growing community of inventors

Toronto, Canada

Francis Paul Buxton