Nestec S.a.

Francia Jacqueline Arce Vera

Serge Andre Dominique Rezzi

Stephane Duboux

Philippe Alexandre Guy

Nicolas Page

Bertrand Bourqui

Francis Foata

Timo Buetler

Yuanlong Pan

Francois-Pierre Martin

Sebastiano Collino

Sunil Kochhar

Marjorie Guitard

Sylvain Lengacher

Pierre Julius Magistretti

Jane Durga

Emma Peré-Trepat

Evelyne Ruchti

Igor Allaman

Stéphane Duboux

Serge André Dominique Rezzi

Françoise-Pierre Martin

The present invention relates generally to the field of enhancing skin appearance. One aspect of the invention aims to provide a composition comprising 4-oxo-2-pentenoic acid for use in the reduction or prevention of regions of the skin with darker pigmentation. The present invention also relates to cosmetic use of a composition comprising 4-oxo-2-pentenoic acid for the reduction or prevention of regions of the skin with darker pigmentation.

4-oxo-2-pentenoic acid and skin pigmentation

The present invention relates generally to compositions with a health benefit. In particular, the invention relates to treatment or prevention of liver disorders. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders. A further subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of liver disorders linked to an insufficient activity of phase II enzymes in the liver.

4-oxo-2-pentenoic acid and liver disorders

The invention provides methods for one or more of preventing or treating sarcopenia and muscle atrophy in animals. The methods comprise administering isoflavones to the animals, preferably in amounts of from about 0.001 to about 10 g/kg/day.

Methods for preventing or treating sarcopenia and muscle atrophy in animals

The present invention relates generally to compositions with a health benefit. In particular, the invention relates to the field of brain health, for example brain protection, maintenance of cognitive function, prevention of cognitive decline and prevention of cognitive disorders. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of cognitive decline.

4-oxo-2-pentenoic acid and brain health

The present invention relates generally to compositions with a health benefit. In particular, the invention relates to the field of cardiovascular disorders, for example, atherosclerosis, high blood pressure, coronary heart disease, myocardial infarction, angina pectoris, stroke, and heart failure. A subject matter of the invention is a composition comprising 4-oxo-2-pentenoic acid for use in the treatment or prevention of cardiovascular disorders.

4-oxo-2-pentenoic acid and cardiovascular health

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Lausanne, Switzerland

Francia Jacqueline Arce Vera