Alma Mater Studiorum-Universitá Di Bologna

Scriba Nanotechnologie S.r.l.

Francesco Zerbetto

Beatrice Fraboni

Luca Prodi

Daniele Alessandro Cauzzi

Massimiliano Cavallini

Fabio Biscarini

Marco Montalti

Sara Bonacchi

Nelsi Zaccheroni

Claudio Franceschi

Nelsi Zacheroni

Matteo Calvaresi

David A Leigh

Gastone Castellani

Stefano Salvioli

Maila Becconi

Stefania Rapino

Daniela Salvatore

Isabella Zironi

Maria Conte

The present invention relates to compositions comprising a polymeric matrix or a gel containing functional enzymes capable of re-creating under culture conditions the cell microenvironment existing in vivo. The present invention also relates to devices for cell cultures comprising such compositions, in particular hydrogel and the use thereof to control the chemical microenvironment of a cell culture or mimic physiological or pathological conditions of the in vivo cells. The compositions and the devices described herein could be also used in vitro for evaluating the therapeutic effect of a compound on a determined cell line or on primary cells.

Compositions, devices and methods for the control in vitro of chemical microambient in cell cultures

Use for measuring temperatures of a coordination complex presenting formula I, wherein M, M, M, M, Mare chosen, each independently of the others, in the group consisting of: Cu, Ag, Au, Pd; n is equal to the sum of the oxidation states of M, M, M, M, Mminus 3; II represents a respective portion of each tridentate ligand having the formula III in which Ris chosen in the group consisting of: Ph, C-Calkyl, halo-alkyl C-Csubstituted phenyl; Ris chosen in the group consisting of: Ph, C-Calkyl, C-Chalo-alkyl-, substituted phenyl; Ris chosen in the group consisting of: C-Calkyl, benzyl, substituted benzyl, C-Chydroxy-alkyl, C-Calkoxy silane. 

Use of a coordination complex or compound for the measurement of temperature

A process for forming nanostructures comprising the step of applying on localised regions of a smooth thin film of bistable or multistable molecules an external perturbation with preset magnitude thereby said film undergoes a collective morphological transformation and nanostructures are formed by selforganisation of said molecules, said nanostructures having preset number, size, interspacing and shape. The nanostructures can be used as storage medium in storage devices.

Process for obtaining spatially-organised nanostructures on thin films

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Bologna, Italy

Francesco Zerbetto