Roquette Freres

Roquette Italia S.p.a.

L'urederra Fundacion Para El Desarrollo Tecnologico Y Social

Novaicos Immunotherapeutics S.r.l.

Trotta, Francesco

Rubin Pedrazzo, Alberto

Francesco Trotta

Roberta Cavalli

Fabrizio Caldera

Paolo Ferruti

Elisabetta Ranucci

Casimiro Luca Gigliotti

Elena Boggio

Umberto Dianzani

Marco Zanetti

Anastasia Anceschi

Giuliana Magnacca

Claudio Fernandez

Ernesto Fossati

Maria Tannous

Monica Argenziano

Annalisa Chiocchetti

Nausicaa Clemente

Chiara Dianzani

Alberto Rubin Pedrazzo

Novel anti-tumor agents comprising at least one ligand of the B7h receptor, wherein the ligand of receptor B7h is loaded in a biocompatible micro- or nano-carrier and is able of binding to receptor B7h and triggering receptor B7h activity.

Anti-tumor therapeutic agents based on B7h receptor ligands

The invention relates to oral administration of biological actives, in particular of insulin, comprising the use of a cross-linked starchy material as a delivery system.

Cross-linked maltodextrins for the oral delivery of biological actives

The invention relates a process for preparing a cross-linked starch-based polymer comprising the following steps: 1) dissolving a starchy material in a suitable solvent to form a starchy material solution; and 2) adding a episulfide of formula (I), wherein R, R, Rand Rare independently selected from hydrogen and (C-C)alkyl in the starchy material solution in order to obtain the disulfide crosslinked starch-based polymer. In another aspect the invention concerns a disulfide-cross-linked starch-based polymer obtainable by the process of the invention, that is characterized by only disulfide bridges.

Cross-linked starch-based polymers for drug-delivery

The invention relates a process for preparing a microporous carbon material comprising the following steps: i) providing a cross-linked polymer obtainable by reacting either A1) a maltodextrin deriving from starch comprising amylose in the range from 25 to 50% expressed as dry weight relative to the dry weight of the starch or A2) a cyclodextrin with an organic aromatic dianhydride in a mass ratio of either maltodextrin or cyclodextrin with respect to the organic aromatic dianhydride in the range of 1:0.50 to 1:2, ii) pyrolyzing at a range from 700 to 900&#xb0; C. with a heating ramp in the range from 5&#xb0; C./min to 30&#xb0; C./min in a inert gas flux; and iii) cooling the obtained residue. The microporous carbon material obtainable by the process of the invention consists of micropores having pore size distribution in the range from about 6 to about 16 &#x212b; and is used as absorber for liquids and gases.

Process for preparing a microporous carbon material and its use as absorption product

Hyperbranched, water-soluble polymers, obtainable by Michael polyaddition of &#x3b1;-, &#x3b2;-, or &#x3b3;-cyclodextrins and amines to bisacrylamides.

Hyperbranched polymers based on cyclodextrins and poly (amidoamines) for the controlled release of insoluble drugs

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Asti, Italy

Francesco Trotta