Medtronic, Inc.

Dialybrid S.r.l.

University Hospital of Basel

Cellec Biotek Ag

Francesco Giovanni Greco

Knud Torp Aundal

Valentina Ilaria Maria Catto

Sebastiao Nicolau Dentinho Van Uden

Davide Meroni

Stefania Adele Riboldi

Marianne Nielsen

Anders Pedersen

Adam Papadimitropoulos

David Wendt

Laura Spinelli

Peter Iwatschenko

Elia Piccinini

Kenneth Jorgensen

Kenneth J&oslash;rgensen

Sebasti O Nicolau Dentinho Van Uden

A hybrid scaffold is disclosed which is made of materials that define peripheral layers designed to interface with the tissues in the implant site and one or more intermediate layers. The materials are combined to give the scaffold mechanical properties suitable for withstanding the stresses of the implant site. The materials are fibroin for the peripheral layers and polyurethane combined with fibroin for each intermediate layer.

Hybrid scaffold suitable for regenerating animal tissues and process for producing the scaffold

A bioreactor for preferably three-dimensional cell culturing comprises a scaffold chamber, a first tube, a second tube and a first valve with a scaffold adapter, a tube adapter and a medium adapter. The first valve has a housing with a longitudinal female portion ending in an opening and a longitudinal actuator being arranged through the opening of the female portion of the housing such that the actuator is arranged partially inside the housing and partially outside the housing, wherein the actuator of the first valve is axially moveable relative to the housing of the first valve between a first position in which the first valve is in the operation position and a second position in which the first valve is in the medium change position. By providing the actuators in the first valve which is applied by axial movements, operation of the bioreactor can be comparably simple and safe.

Bioreactor and rack for mounting bioreactors

A catheter system is disclosed including an elongated catheter, an elongated balloon carrier and a disposable balloon formed from an expandable and resilent biocompatible material. The balloon has a lumen disposed between a proximal end and a distal end thereof. The proximal end of the carrier and the distal end of the catheter are configured to permit the distal end of the catheter to matingly engage the proximal end of the carrier. The outer diameter of the balloon carrier and the outer diameter of the balloon are configured such that the diameter of the carrier and the diameter of the balloon permit the balloon first to be slideably mounted onto the balloon carrier and second to be slideably moved from the carrier onto the catheter when the proximal end of the carrier is matingly or otherwise suitably engaged with the distal end of the catheter.

Catheter system having disposable balloon

A disposable balloon catheter and corresponding catheter system are disclosed. In one embodiment, the catheter system comprises: (a) an elongated catheter comprising a first outer diameter, a first proximal end and a first distal end; (b) an elongated balloon carrier having a second proximal end, a second distal end and a second outer diameter, the second proximal end of the carrier and the first distal end of the catheter being configured to permit the first distal end of the catheter to matingly engage the second proximal end of the carrier, the second outer diameter of the balloon carrier being similar to the first outer diameter of the catheter; and (c) a disposable balloon formed from an expandable and resilient biocompatible material, the balloon having a lumen disposed between a third proximal end and a third distal end thereof, the lumen having at least a third inside diameter.

Growing community of inventors

Cantu, Italy

Francesco Giovanni Greco