Ecole Polytechnique Federale De Lausanne

Ecole Polytechnique Féderale De Lausanne (epfl)

Xsensio Sa

Francesco Bellando

Mihai Adrian Ionescu

Erick García Cordero

Fabien Patrick Wildhaber

Johan Frédéric Longo

Hoël Guerin

Hoël Maxime Guérin

Erick Garcia Cordero

Junrui Zhang

Ali Saeidi

The present disclosure concerns a Field-Effect Transistor device or sensor comprising at least one drain region, at least one source region, at least a channel region, at least a first gate connected to the channel region, at least one stack comprising at least one metal layer or metal extension and at least one via layer or via extension; or a plurality of alternating (i) metal layers or metal extensions and (ii) via layers or via extensions, at least one second gate or second layer connected to the at least one first gate by the at least one stack, the at least one second gate or second layer permitting sensing of ions, and/or molecules and/or biomarkers, and at least one microfluidic channel or structure connected to or provided on the at least one second gate or second layer.

Field-effect transistor device or sensor for sensing ions, molecules or biomarkers in a fluid

An on-body wearable bio-fluid collection and sensing device including an interface or interface surface comprising at least one biocompatible material for contacting a bodily part; at least one inlet for receiving the bio-fluid, at least one outlet for evacuating the bio-fluid, a plurality of semiconductor sensors configured to analyze the received bio-fluid, at least one reference electrode for biasing a bio-fluid gate of at least one of the semiconductor sensors, and at least one micro-fluidic or nano-fluidic channel in fluid communication with the at least one inlet, the at least one outlet and the at least one reference electrode; the at least one micro-fluidic or nano-fluidic channel includes the plurality of semiconductor sensors.

Bio-fluid collection and sensing device, system and method

Presented herein are devices for collecting and/or channeling a biofluid (e.g., sweat, tears, saliva) and detecting and/or quantifying one or more biomarkers in the biofluid. The one or more biomarkers may include, for example, ions, salts thereof, hormones and/or steroids, proteins, metabolites and organic compounds. In certain embodiments, the devices described herein include a specially designed interface and a zero-energy micro pump that allow the device to be comfortably affixed directly to the skin of a user while biofluid is efficiently and non-invasively collected from the skin of the user. In certain embodiments, the biofluid collection and sensing device is housed on or in another wearable device, such as a wrist band or a smart watch. In certain embodiments, the devices described herein are disposable (e.g., after a certain period of use and/or wear the device can be disposed and replaced with a low-cost replacement).

Apparatus for non-invasive sensing of biomarkers in human sweat

A semiconductor sensor includes a source element; a drain element; and a semiconductor channel element between the source element and the drain element, forming an electrically conductive channel. An insulator is positioned between the semiconductor channel element and a solution to be sensed. A reference contacts the solution and sets an electric potential of the solution. A bias voltage source generates an external sensor bias voltage for electrically biasing the reference electrode. A sensing surface interacts with the solution comprising analytes for generating a surface potential change at the sensing surface dependent on the concentration of analytes. The sensor further includes a ferroelectric capacitance element between the insulator and the bias voltage source for generating a negative capacitance for a differential gain between the external sensor bias voltage and an internal sensor bias voltage sensed at a surface of the channel element facing the insulator or ferroelectric capacitance element.

Negative capacitance semiconductor sensor

Growing community of inventors

Renens, Switzerland

Francesco Bellando